ANTIBIOTICS DRUG C Flashcards
He discovered the mold that produced Penicillin.
Alexander Fleming
Amount of antibacterial drug to halt the growth of microorganism.
MEC or Minimum Amount of Concentration.
Give the five mechanisms of Antibacterial Actions. Accordingly
I. Inhibition of bacterial cell wall synthesis.
Give the five mechanisms of Antibacterial Actions. Accordingly .
II. Alteration of membrane permeability.
Give the five mechanisms of Antibacterial Actions. Accordingly
III. Inhibition of protein synthesis.
Give the five mechanisms of Antibacterial Actions. Accordingly
IV. Inhibition of the synthesis of bacteria RNA and DNA
Give the five mechanisms of Antibacterial Actions. Accordingly
V. Interference with metabolism within the cell.
Give the minimum inhibitory concentration of Ampicillin.
16
Give the minimum inhibitory concentration of Ceftazidime.
4
Give the minimum inhibitory concentration of Amoxicillin/Clavulanic Acid
8
Give the three General Adverse Reactions to Antibacterial Drugs.
Allergy or Hypersensitivity
Superinfection
Organ Toxicity
Equal to the sum of the effects of two antibiotics.
Additive Effect
When two drugs are used together, the desired effect may be greatly reduced.
Antagonistic Effect
Occurs when one antibiotics increases the effectiveness of the 2nd drug.
Potentiative Effect
Primarily effective against one type of organism (selective).
Narrow Spectrum
Effective against gram-positive and gram negative organisms.
Broad Spectrum
When sign and symptom do not improve.
Subtherapeutic
When a drug selected is known to be the best drug that can kill the MO.
Empiric Therapy
Occurs when the antibiotics reduce or completely eliminate the normal bacterial flora.
Superinfection
It is a bioassay performed on the skin which detects presence of allergen specific IgE on a patients masts cells.
Skin testing / Skin Test
