antibiotics Flashcards
1
Q
mechanism of antimcrobial resistance
A
antimicrobial cannot get in
eg- in gram negative bacteria
cell wall is complex it has an outer membrane gets rid of efflux pumps and porins
2
Q
antimicrobial degraded
A
antimicrobe is destroyed by enzyme release by bacteria
e.g beta lactams
3
Q
mutation in target site
A
drug gets in but cant bind to receptor because it has been mutated
eg quinolones, macrolides, penicillin
4
Q
transferable DNA
A
plasmids and transposons
5
Q
common cause of community acquired pneumonia
A
strep pneumonia
gram neg bacilli
Neisseria gonorrhoea
6
Q
common cause of hospital acquired pneumonia
A
staph which is resistant to cloxacillin
gram negs resistant to beta lactams
