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Pharma drugs > Antibiotics > Flashcards

Antibiotics Flashcards

1
Q

Beta-lactame antibiotics

A
  • Penicillins
  • Beta-lactamase inhibitors
  • Cefalosporins
  • Carbapenes
  • Monobactams
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2
Q

Penicillins

A
  • Narrow spectrum penicillins
  • Penicillinase resistant penicillins
  • Broad spectrum antibiotics
  • Antipseudomonas penicillins
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3
Q

Narrow spectrum penicillins

A
  • Benzylpenicillin Na, K
  • Procaine, benzathine benzylpenicillin
  • Phenoxymethylpenicillin
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4
Q

Penicilllinase resistant penicillin

A
  • Oxacillin
  • Cloxacillin
  • Dicloxacillin
  • Flucloxacillin
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5
Q

Broad spectrum antibiotics

A
  • Amoxicillin

- Ampicillin

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6
Q

Antipseudomonas penicillin

A
  • Piperacillin

- Ticarcillin

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7
Q

Beta-lactamase inhibitors

A
  • Clavulanic acid
  • Sulbactam
  • Tazobactam
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8
Q

Cefalosporin 1.generation

A
  • Cefazolin
  • Cefapirin
  • Cefadroxil
  • Cefalexin
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9
Q

Cefalosporin 2.generation

A

-Cefuroxime

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10
Q

Cefalosporin 3.generation

A
  • Ceftiofur
  • Cefovecin
  • Ceftriaxone
  • Cefotaxime
  • Ceftazidine
  • Cefoperazon
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11
Q

Cefalosporin 4.generation

A

-Cefquinome

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12
Q

Carbapenems

A
  • Imipenem

- Meropenem

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13
Q

Monobactams

A
  • Aztreonam

- Tigemonam

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14
Q

Aminoglycosides

A
  • Streptomycin
  • Neomycin
  • Gentamicin
  • Spectinomycin
  • Kanamycin
  • Tobramycin
  • Apramycin
  • Amikacin
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15
Q

Tetracyclines

A
  • Tetracycline
  • Chlortetracycline
  • Oxytetracycline
  • Docycyline
  • Minocycline
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16
Q

Macrolides

A
  • Erythromycin
  • Azithromycin
  • Clarithromycin
  • Spiramycin
  • Tylosin
  • Tylvalosin
  • Tilmicosin
  • Tulathromycin
  • Gamithromycin
  • Tildipirosin
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17
Q

Lincosamides

A
  • Clindamycin

- Lincomycin

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18
Q

Pleuromutilins

A
  • Tiamulin

- Valnemulin

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19
Q

Phenicols

A
  • Florfenicol
  • Chloramfenikol
  • Thiamphenicol
20
Q

Peptide antibiotics

A
  • Polypeptide

- Glycopeptide

21
Q

Polypeptide antibiotics

A
  • Bacitracin
  • Polymyxin B
  • Colistimethate
22
Q

Glycopeptide Antibiotics

A
  1. gen
    - Vancomycin
    - Teicoplanin
    - Ramoplanin
  2. gen
    - Oritavancin
    - Dalbavancin
    - Telavancin
23
Q

Rifamyicins

A

Rifampin

Rifabutin

24
Q

Mupirocin

A

Mupirocin

25
Q

Fosfomycin

A

Fosfomycin

26
Q

Sulphonamides

A

-Sulfadimidine
-Sulfadiazine
-Sulfachlorpyridazine
-Sulfachlorpyrazine
-Sulfamethoxazole
-Sulfadoxine
-Sulfaquinoxaline
-Sulfasalazine
Local:Sulfacetamide, sulfguanidine
Original:Prontosil

27
Q

Diaminopyrimidines

A
  • Baquiloprim

- Trimethoprim

28
Q

Nitrofurans

A
  • Nitrofurantoin

- Furazolidone

29
Q

Nitroimidazoles

A
  • Ronidazole
  • Metronidazole
  • Tinidazole
30
Q

Fluoroquinolones 1.generation

A

-Nalidixic acid

31
Q

Fluoroquinolones 2.generation

A
  • Flumequine
  • Norfloxacin
  • Ciprofloxacin
  • Enrofloxacin
  • Danofloxacin
  • Difloxacin
  • Marbofloxacin
32
Q

Fluoroquinolones 3.generation

A
  • Sparfloxacin

- Levofloxacin

33
Q

Fluoroquinolones 4.generation

A
  • Pradofloxacin

- Moxifloxacin

34
Q

Bactericidals

A
  • Penicillin
  • Cephalosporin
  • Aminoglycosides
  • Fluoroquinolones
  • Polypeptides(glycopeptide bacteriostatic against enterococci, timedependent)(polymyxin conc dep)
  • Rifamycin
  • Quinoxaline
35
Q

Bacteriostatics

A
  • Tetracyclines(bactericidal at high conc in urine)
  • Macrolides(bactericidal in the lungs at high conc)
  • Lincosamides
  • Phenicols
  • Pleuromutilins
  • Sulphonamides
  • Diaminopyrimidines
36
Q

Inhibit 30 S ribosome subunit

A
  • Aminoglycosides

- Tetracyclines

37
Q

Inhibit 50 S ribosome subunit

A
  • Macrolids
  • Lincosamides
  • Pleuromutilins
  • Phenicols
38
Q

Affecting cell wall synthesis

A
  • beta-lactams
  • Vancomycin
  • Bacitracin
  • Glycopeptides(inhibit peptidoglycan synthesis)
  • Polypeptids(Acts as detergent)
39
Q

Affect DNA/RNA syntesis

A

RNA-Rifamycin
DNA-Fluoroquinolones
DNA and ribosome-Nitrofurans
Toxic metabolites destroy DNA-Nitrimidazoles and quinoxaline

40
Q

Folic acid synthesis

A
  • Sulphonamides-compete with paba for the active site

- Diaminopyrimidines-inhibit tetrahydrofolic acid synthesis

41
Q

Hydroxyquinolones

A
  • Clioquinol
  • Iodoquinol
  • Chloroquinaldole
  • Broxyquinoline
  • Hydroxyquinoline
42
Q

Quinoxaline

A
  • Carbadox
  • Olaquindox
  • Quindoxin
  • Cyadox
43
Q

Inhibit CYP450

A
  • Macrolides

- Pleuromutilins

44
Q

Induce CYP450

A

Rifamycin

45
Q

BBB penetration

A
  • Sulphonamides
  • Diaminopyrimidines
  • Phenicols(?)
  • Fluoroquinolones(not 1st gen)
  • Nitroimidazoles

Pharma drugs (4 decks)

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