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HYMS Block 9 > Antibiotics > Flashcards

Antibiotics Flashcards

1
Q

What is the MOA of beta lactams?

A

inhibit PBPs therefore prevent transpeptidation

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2
Q

Name 6 examples of beta lactams

A 
amoxycillin
methicillin
cephuroxime
benzylpenicillin
cephalosporin
carbapenems
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3
Q
  1. What is the MOA of glycopeptides?
  2. Which bacteria are glycopeptides used to treat?
  3. Name an example of a glycopeptide
  4. Name 2 infections that this drug is used to treat
A
  1. binds to the terminal end of the growing peptidoglycan chain
  2. gram positive
  3. Vancomycin
  4. MRSA and C. diff associated diarrhoea
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4
Q

What is the MOA of aminoglycosides?

A

30s ribosome inhibitors

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5
Q

Name 3 examples of aminoglycosides avd what they are used to treat

A
  • gentamycin - broad spectrum
  • metronidazole - C diff associated diarrhoea
  • streptomycin - TB
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6
Q

What is the MOA of tetracyclines?

A

30s ribosome inhibitors

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7
Q

Name 2 examples of tetracyclines

A
  • doxycycline (used to treat pneumonia)

- erythromycin (also inhibits 50s ribosomes - macrolide)

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8
Q

What is the MOA of Macrolides?

A

50s ribosome inhibitors

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9
Q

Name 2 examples of macrolides

A
  • erythromycin

- clarythromycin

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10
Q

What is the MOA of fusidic acid?

A

inhibits Elongation Factor G

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11
Q

What is the MOA of sulphonamides

A

competitively inhibits PABA

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12
Q

give an example of a sulphonamide

A

Suxamethoxazole

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13
Q

What is the MOA of trimethoprim

A

inhibits DHF reductase

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14
Q

What is the MOA of quinolones?

A

inhibit DNA replication

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15
Q

Name an example of a quinolone

A

ciprofloxacin

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16
Q

What is the MOA of Rifamycins?

A

inhibit RNA synthesis

17
Q
  1. Name an example of a Rifamycin

3. Name three things that this is used to treat

A
  1. Rifampicin

2. TB, Legionnaire’s. menningococcus

18
Q

What is the MOA of polymixins?

A

Acts as membrane detergent

19
Q

Name an example of a polymixin

A

colistin

HYMS Block 9 (9 decks)

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