Antibiotics

Question 1

Aminopenicillins ABs

Answer 1

• ampicillin
• amoxicillin

*increased binding to PBP and increased penetration through gram - membrane

Question 2

Penicillinase Resistant Penicillins ABs

Answer 2

• methicillin
• nafcillin
• oxacillin
• dicloxacillin

MOND

Question 3

Antipseudomonal penicillins ABs

Answer 3

• carboxypenicillins
  
  • ticarcillin
  • carbenicillin
• ureidopenicillins
  
  • piperacillin (only one in U.S.)
  • mezlocillin

Ctc; Upm

Question 4

Penicillin G coverage

Answer 4

gram +: s. pyogenes, s. pneumoniae, Viridans group strep

gram -: N. meningitidis, spirochetes (T. pallidum), non beta lactamase producing anaerobes (C. perfringens)

Question 5

Aminopenicillins coverage

Answer 5

gram +:

gram -: E. coli, Proteus, Salmonella, Shigella

with BL inhibitors: H. influenzae, Klebsiella, Proteus, B. fragilis

Question 6

Penicillinase Resistant Penicillin coverage

Answer 6

gramt +: poor

gram -: S. aureus, S. epidermidis (staphylococcal species)

Question 7

Antipseudomonal Penicillin coverage

Answer 7

gram +:

gram -: P. aeruginosa, Klebsiella pneumoniae, H. influenzae, E. coli, B. fragilis