antibiotics Flashcards

1
Q

What is an antibiotic?

A

-chemical substance that is produced by microorganisms and has the capacity in dilute solution to selectively inhibit the growth or kill other microorganisms

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2
Q

antimicrobial/ antibacterial

A

-any substance of natural, semisynthetic or synthetic origin that kills or inhibits the growth of microorganisms/bacteria but causes little to no damage to the host

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3
Q

T/F: all antimicrobials are antibiotics but not all antibiotics are antimicrobials

A

FALSEEE: all antibiotics are antimicrobials but not all antimicrobial are antibiotics

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4
Q

uses for antimicrobials in animals

A
  • therapeutic use: when diseased animals are treated
  • prophylactic use: healthy herds or animals are treated to prevent infection
  • metaphylactic use: diseased herds are treated to cure infection in some individuals and prevent infection in others
  • growth promotion: used in healthy animals in sub-therapeutic concentrations to improve growth rate, efficiency of feed utilization, and reproductive performance
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5
Q

classification of antibacterials

A
  1. chemical structure
  2. origin (natural vs. synthetic)
  3. effect on bacteria (bacteriostatic vs. bactericidal)
  4. spectrum of activity (broad spectrum vs narrow spectrum)
  5. mode of action
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6
Q

penicillins (beta lactam)

A
  • Penicillin G/V
  • ampicillin/amoxicyllin
  • amoxicillin/ clavulanic acid
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7
Q

tetracyclines (beta lactam)

A
  • tetracycline
  • oxytetracycline
  • doxycycline
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8
Q

quinolones (beta lactam)

A
  • oxolinic acid
  • enroflaxacin/marbofloxacin
  • pradofloxacin norfloxacin
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9
Q

sulfonamides (beta lactam)

A
  • sulfiadiazine

- sulfadiazine/trimethoprim

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10
Q

phenicols (beta lactam)

A
  • chloramphenicol

- florfenicol

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11
Q

cephalosporins (beta lactam)

A
  • cefalexin/cephadroxil
  • cefpodoxime/ceftiofur
  • cefovecin, cefquinome
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12
Q

macrolides (beta lactams)

A
  • erythromycin

- tiamulin, tilmicosin

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13
Q

lincosamides (beta lactams)

A

-lycomycin/clindamycin

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14
Q

aminoglycosides (beta-lactams)

A
  • streptomycin
  • gentamicin/neomycin
  • amikacin
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15
Q

polypeptides (beta-lactams)

A

colistin/polymixin

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16
Q

misc beta-lactams

A

-metronidazole

17
Q

carbapenems (beta-lactams)

A
  • not authorized for vet use
  • imipenem/meropenem
  • ertapenem/doripenem
18
Q

glycopeptides (beta lactams)

A
  • not for vets

- vancomycin/teicoplanin

19
Q

oxazolidinones (beta lactams)

A
  • not for vets

- linezolide

20
Q

natural antibiotics

A

-produced by fungi and bacteria

21
Q

semi-synthetic antibiotics

A

-chemically altered natural compounds

22
Q

synthetic antibiotics

A

-chemically designed by man