Antibiotics Flashcards
1
Q
Aminoglycosides
A
These prevent initiation of translation. Used with beta lactam.
2
Q
What is the antibotic that blocks transcription?
A
Rifamycins: These bind and block rna polymerase and prevent elongation. They are bacterial killers and are useful in treating tuberculosis.
3
Q
Tetracycline
A
blocks the attachment of tRNA to the ribosome. Broad spectrum. Bacteriostatic- slow growth or stop growth
4
Q
Macrolides
A
blocks elongation during translation. Blocks the exit hole and the pressure will bust the protein open. Broad spectrum
5
Q
Quinolones
A
Inhibits bacterial Topoisomerase or DNA gyrase.
6
Q
Rifamycins
A
Bind & blocks RNA polymerase preventing initiation/elongation.
7
Q
Aminoglycosides
A
Block the initiation of translation and cause misreading of mRNA
