Antibiotics Flashcards
0
Q
Rifamycin
A
Inhibits DNA-dependant RNA synthesis by binding to prokaryotic RNA polymerase
1
Q
Antinomycin
A
Bonds DNA at transcription initiation complex and stops elongation by RNA polymerase
2
Q
Streptomycin
A
Affects initiation (30S subunit) and causes misreading of codons
3
Q
Erythromycin
A
Bonds to 50S subunit and prevents translocation
4
Q
Chloramphenicol
A
Inhibits peptidyl transferase by binding to 50S subunit
5
Q
Tetracyclines
A
Inhibit binding of aminoacyl-tRNAs to the ribosome
6
Q
Puromycin (affects eukaryotes too)
A
Causes premature chain termination during translation (pro & eukar.)
7
Q
alpha-aminitin (actually a toxin)
A
Inhibits RNA polymerase II (deadly toxin)
8
Q
Diphtheria toxin (not a drug)
A
Inhibits RNA translation by inactivating eukaryotic EF-2
