Antibiotics Flashcards
All macrolides inhibit CYP450 except?
Azithromycin
has the highes Vd and slowest elimination
SE Toothenamel dysplasia/discoloration
TeTracycline
(Blocks aTTachment of Trna to acceptor site
Drug used for Macrolide resistance
Telithromycin
________ for anaerobic infxns ABOVE
________ for anaerobic infxns BELOW
Clindamycin
Metronidazole
Post antibiotic effect are seen in?
Aminoglycosides and Flouroquinolones
Narrowest therpeutic window among Aminoglycosides
Amikacin
Aminoglycoside that can cause Hepatic Encepalopathy
Neomycin
Most ototoxic Aminoglycoside
Kanamycin, Amikacin
For drug resistant Gonorrhea or penicillin allergies
Spectinomycin
Most vestibulotoxic
Tobramycin, Gentamycin
Drug that reaches high concentration in Prostatic and Vaginal fluid
Trimethoprim
Inhibitor of Dihydroptoate synthase
Inhibitor of Dihydrofolate Reductase
Sulfonamides
Trimethoprim
Dihydropteroate Synthase inhibitor used for BuRNs
Sliver Sulfadiazine
SE Bone Cartilage damage
Flouroquinolones
Ciprofloxacin
Widest spectrum of activity in Flouroquinolones
Moxifloxacin