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Year 1 Medicine > Antibiotics > Flashcards

Antibiotics Flashcards

1
Q

Glycopeptides

A

Vancomycin
- disrupt cell wall construction

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1
Q

b-Lactams

A

Penicillins
Carbapenems
Cephalosporins
- peptidoglycan synthesis

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2
Q

Anti-folates

A

Sulfamethoxazole
Trimethoprim
- prevent folate synthesis for DNA production
- causes NTD in pregnancy!!

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3
Q

Macrolides

A

Erythromycin (broad spread)
- disrupt 70s ribosomes needed for protein synthesis

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4
Q

Tetracyclines

A

Oxytetracycline (broad spectrum)
- disrupt 70s ribosomes needed for protein synthesis
- liver damage in pregnant women!!
- teeth discolouration in children!!

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5
Q

Aminoglycosides

A

Streptomycin
Gentamycin
- disrupt 30s ribosomes needed for protein synthesis
- nephrotic ototoxicity!!

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6
Q

Quinolones

A

Ciprofloxacin
Levofloxacin
- disrupt DNA synthesis
- cartilage damage!!

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7
Q

Polymyxin

A

Polymyxin B
- disrupts cell membrane
- v. high toxicity!! (last resort or administered topically)

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Year 1 Medicine (3 decks)

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