Antibiotics

Question 1

MOA: Beta-lactams
(e.g. Penicillin)

Answer 1

Inhibit cell wall synthesis

Question 2

MOA: Macrolides
(e.g. Erythromycin)

Answer 2

Inhibit protein synthesis at the 50S subunit

Question 3

MOA: Lincosamides
(e.g. Clindamycin)

Answer 3

Inhibit protein synthesis at the 50S subunit

Question 4

MOA: Chloramphenicol

Answer 4

Inhibit protein synthesis at the 50S subunit

Question 5

MOA: Tetracyclines
(e.g. Doxycycline)

Answer 5

Inhibit protein synthesis at the 30S subunit

Question 6

MOA: Aminoglycosides
(e.g. Gentamicin)

Answer 6

Inhibit protein synthesis at the 30S subunit

Question 7

MOA: Trimethoprim

Answer 7

Inhibits nucleic acid synthesis - specifically purine

Question 8

MOA: Quinolones
(e.g. Ciprofloxacin)

Answer 8

Inhibits DNA gyrase to prevent supercoiling

Question 9

MOA: Metronidazole

Answer 9

Inhibits DNA synthesis

Question 10

MOA: Rifampicin

Answer 10

Inhibits DNA dependent RNA polymerase - blocks RNA transcription

Question 11

MOA: Glycopeptides
(e.g. Teicoplanin, Vancomycin)

Answer 11

Inhibit late-stage peptidoglycan cell wall assembly