Antibiotics Flashcards

1
Q

Flora such as staphylococci, streptococci,

pneumococci, and Haemophilus influenzae are commonly found where?

A

Upper respiratory tract

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2
Q

These flora: escherichia coli, Klebsiella, Enterobacter, Proteus,
Pseudomonas, Bacteroids, clostridia, lactobacilli, strep, and staph are found where?

A

Colon

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3
Q

These drugs kill organisms

A

Bactericidal

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4
Q

These drugs inhibit growth of organisms

A

Bacteriostatic

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5
Q

Drugs are classified based on what two factors?

A

Classified by their chemical structure or by their mechanism of
action

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6
Q

Used to prevent or treat infections caused by pathogenic microorganisms

A

Antimicrobials

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7
Q

These drugs are effective against a wide

variety of microorganisms

A

Broad-spectrum

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8
Q

These drugs are effective against one or a

restricted group of microorganisms

A

Narrow-spectrum

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9
Q

signs/symptoms: Tinnitus , vertigo, hearing loss

A

Ototoxicity

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10
Q

Your pt has Jaundice, dark urine, pale stools, abdominal pain, fever and Monitor liver function tests

A

Hepatoxicity

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11
Q

Aminoglycosides can cause?

A

ototoxicity and nephrotoxicity

-Accumulate in kidneys and ears

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12
Q

Your pt is a 16 year old who was told to take Fluoroquinolones. Is this safe?

A

NO! Contraindicated in children under 18 yo

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13
Q
Penicillins
• Penicillin (P)
• Cephalosporins
• Cefotaxime (P)
• Vancomycins
• vancomycin
• Carbapenems
• Meropenem
• Monobactam Antibiotics
all effect what part of the cell?
A

They all effect the bacterial cell wall

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14
Q

This drug is a combination for beta lactamase

A

Zosyn (piperacillin/taxobactam)

-is a penicillin

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15
Q

Keflex (cephalexin), Ancef (kefzol), and

Maxipime (cefepime) are what group of drugs

A

Cephalosporins: Treat infections of the respiratory tract, skin, bone and joints,
urinary tract, brain and spinal cord

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16
Q

Primaxin (imipenemcilastatin) is what type of drug?

A

Carbapenems: Broad spectrum, bactericidal, beta-lactam anti-microbials
• Inhibit synthesis of cell walls.
• All are parenteral
• Indicated for organisms resistant to other drugs

17
Q
Aminoglycosides
• Gentamicin (P)
Tetracyclines
• Tetracycline (P)
Macrolide Antibiotics
• Erythromycin (P)
Are all drugs that have what effect on a cell?
A

They are all antibiotics that effect protein synthesis

  • Aminoglycosides are Bactericidal agents, a narrow spectrum drug, used to treat gram negative organisms:
  • pneumonia
  • MRSA
  • Skin infections/UTI’s
  • Sepsis
18
Q

Fluoroquinolone use will have what negative side effect on you pts under 18 years of age?

A

Effects cartilage and can cause tendon ruptures.

19
Q

Examples of fluoroquinolones include?

A

Cipro (ciprofloxacin), Levaquin

levofloxacin) , Floxin (ofloxacin
* look for the “floxacin”

20
Q

These drugs are Synthetic bactericidal drugs with activity against gram positive
and gram negative organisms
• Most are given orally
• Excreted via kidneys

A

fluoroquinolones

21
Q

What effects can antibiotics have on patients that will interfere with rehab?

A
GI problems
Anemia – limits exercise tolerance
Dizziness and vertigo
Hearing loss
Tendonitis
Skin rashes
• Need to be reported
22
Q

Your patient has HSV, Herpes zoster. What drug are they most likely taking?

A

Acycolvir (Anti-Viral drug): It is an anti-herpes agent

23
Q

Your patient is on an antiviral and tells you they are taking NSAIDS for their pain. Is this good or bad? Education?

A

Its a bad combination: Nephrotoxicity

• Avoid concurrent use of NSAIDs

24
Q

Fluconazole or itraconazole and Ketoconazole is an antifungal drug often used to treat?

A

Coccidioidomycosis (Valley Fever)
• Symptomatic infections (40% of cases) usually present as flu-like illness
with fever, cough, headaches, rash, and myalgias

25
You let loose a little too much in undergrad and got the Chlamydia, oh no! what do you take?
Tetracycline - Broad spectrum bacteriostatic - Treatment of uncomplicated urethral, endocervical or rectal infections caused by chlamydia
26
Some asshole got MRSA, he started taking medication but now he is all red and shit, hypotensive, skin rash and flushes. What drug was this dude taking?
Vancomycin -Can cause "red man syndrome" if given too quickly • Caution in patients with myasthenia gravis • May worsen symptoms