antibiotics Flashcards
what is the MOA of vancomycin (vancocin)?
inhibits bacterial cell wall synthesis
bactericidal
what gram is vancomycin (vancocin)?
gram +
what is vancomycin (vancocin) used for?
used for c.diff and MRSA skin infections
how is vancomycin (vancocin) administered for c.diff?
PO
how is vancomycin (vancocin) administered?
PO, IV
what are the potential AE of vancomycin (vancocin)?
NORMS
nephrotoxic, ototoxic, red man syndrome, (rash, hypotension), mild hypotension, skin allergy, decreased c/o
what does NORMS stand for?
nephrotoxic
ototoxic
red man syndrome
mild hypotension
skin allergy
is vancomycin (vancocin) bacteriostatic or bactericidal?
bactericidal
what gram positive anaerobe is resistant to metronidazole?
c.diff
what antibiotic is for MRSA?
vancomycin (vancocin)
what gram is c.diff?
gram +
what bacteria is c.diff?
spore forming
who is at the highest risk for c.diff?
-recent antibiotic use
-elderly
-gi surgery
-prolonged illness
- immunocompromised
what does c.diff look like?
foul smelling multiple stools
which antibiotics use has c.diff risk?
clindamycin,
2/3 gen cephalosporins
fluoroquinolones
what MOA is Fosfomycin (monourol)?
inhibits cell wall synthesis by disrupting peptidoglycan strands.
what gram is Fosfomycin (monourol)?
gram negative
what potential AE does gram negative have?
n/d/HA and vaginitis
how is Fosfomycin (monourol) administered?
single dose oral therapy in a powder
what bacteria contributes to UTI?
e.coli and faecalis
what activity does Fosfomycin (monourol) have?
e.coli and faecalis and gram negative
what uses is Fosfomycin (monourol)?
uncomplicated UTI in females
is Fosfomycin (monourol) only for female UTI?
yes
