Antibiotics Flashcards
Strep Pneumonia Gram Stain
+
Morazella Catarrhalis Gram Stain
-
Haemophillus Influenzae Gram Stain
-
Mycoplasma Pneumonia Gram Stain
Neither - no cell wall
Strep Pyogenes Gram Stain
+
Staph Aureus Gram Stain
+
E coli Gram Stain
- (anaerobe)
Staph Saprophyticus Gram Stain
+
Klebsiella Sp Gram Stain
- (anaerobe)
Proteus Mirabilis Gram Stain
- (anaerobe)
Chlamydia Trachomatis Gram Stain
-
Neisseria Gonorrhea Gram Stain
-
Trichomonas Vaginalis Gram Stain
Neither - protozoa
Gardnerella Vaginallis gram stain is variable
Variable?
Neisseria Meningitidis Gram Stain
-
Campylobacter jejuni Gram Stain
-
Giardia lamblia Gram Stain
neither - protozoa
GI tract causative organisms
Campylobacter & Giardia
CNS causative organisms
Neisseria Meningitidis
Genital tract causative organisms
Chlamydia, gonorrhea, trichomonas vaginalis, gardnerella vaginalis
Urinary tract causative organisms
E.coli, klebsiella, proteus mirabilis, staph saprophyticus
Skin causative organisms
Strep pyogenes (also tonsils), staph aureus
LRT pneumonia causative organisms
Mycoplasma pneumoniae
URT, Ears, Sinuses, LRT causative organisms
Haemophilus influenzae, strep pneumoniae, moraxella catarrhalis
B lactams mechanism
Interfere with cell wall synthesis
Two types of B lactams
Penicillins, cephalosporins
Types of penicillins (4)
Penicillin, flucloxacillin, amoxicillin, amoxicillin + clavulanic acid (augmentin)
Augmentin mechanism
Clavulanic acid is B lacatmase inhibitor therefore broader spectrum
Cephalosporins example 2nd gen
Cefuroxime
Cephalosporin example 3rd gen
Ceftriaxone
Cephalosporin as increase generation
Move from predominantly +ve to -ve cover
Macrolides mechanism
Inhibit bacterial protein synthesis
Macrolides examples (3)
Erythromycin, azithromycin, roxithromycin
Macrolides are good for
A wide spread of activity including mycoplasma, not good for H, flu
Quinolones mechanism
Inhibit bacterial DNA replication
Quinolones examples (1)
Ciprofloxacin
Quinolones broad or narrow
Broad - avoid if possible
Sulphonamides mechansim
Inhibit bacterial folic acid synthesis
Sulphonamide example
Trimethoprim (+sulfamethoxazole)
Trimethoprim + Sulfamethoxazole name
Co-trimoxazole
Trimethoprim only used alone in
UTIs
Tetracyclines mechanism
Inhibit bacterial protein synthesis
Tetracyclines examples (2)
tetracycline, doxycycline
Nitrofurantoin why good in UTI
Concentrates in urine
Imidazoles example (1)
Metranidazole
Imidazoles good for
Treatment of anaerobic infections & protozoa
Strep throat site and severity
Pharynx & tonsils & can’t swallow (sames as EPV)
Strep throat Tonsils vs EPV
large, red, may have pus
EPV - same but larger, pseudomembrane
Strep throat timecourse
Aprupt onset, starts and stays in throat
Strep throat lab
Bacterial swab, neutrophilia (mild)
EPV lab
Lymphocytosis
LN strep throat vs EPV
juguladigastric vs posterior triangle
Liver & spleen Strep throat vs EPV
Strep no abnormalities, EPV may be enlargeed or tender
RF high risk if
maori or pacifika, young, crowded housing, low SES
Otitis media most common causative organisms
Moraxella catarrhalis, strep pneumonia, haemophilus influenza
or virus - influenza virus, rhinovirus, RSV
Otitis media antibiotic & why
Amoxicillin - effective against gram -ve & +ve
Otitis media antibiotic alternative options if allergy
Erythromycin, cefuroxime
UTI first line treatment
Nitrofurantoin
UTI treatment not effective why?
Resistance, not sensitive, non-compliance, mis-diagnosis (STI, pyelonephritis)
Injury red streaks
Lymphaginitis
Gardening injury think about
Tetanus
Skin infection treatments
flucloxacillin
Impetigo caused by
Staph aureus or strep pyogenes
Impetigo treatment
Flucloxacillin
Antiseptic cream, test swab for sensitivities
Impetigo not responding to treatment instead give(check)
Co-trimoxazole
COPD exacerbations caused by
Strep pneumoniae, haemophilus influenzae, moraxella catarrhalis
COPD treat with
Amoxicillin
+ bronchodilators, steroids
then augmentin if not responding, allergy - doxycline
Chlamydia treatment
Doxycline
Chlamydia treatment in pregnancy
Azithromycin
Sinusitis causative organisms
Strep Pneumoniae, Haemophilus influenzae, moraxella catarhalis
or Virus - rhinovirus etc
Sinusitis antibiotic
Amoxicillin
Sinusitis when to treat
> 10 days, often self resolving
Strep throat treatment & length
10 days oral penicillin
Explaining a medication key points
How it works, side effects & what to do about them, how & when to take it, when to stop taking it.
Bite on skin
augmentin
Ask about when prescribing antibiotics
pregnancy & allergy
Sinusitis treatment
Amoxicillin only if 10 days as usually viral, otherwise rest, fluids, paracetamol
Meningitis antibiotic
ceftriaxone
Impetigo treatment
Antiseptic then if reoccurs flucloxacillin
Chlamydia treatment
1 gm stat azithromycin