Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

MicroBio > Antibiotics > Flashcards

Antibiotics Flashcards

1
Q

Penicillin General

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Pencillin G

A
  1. First gen
  2. treats: gram postive, enteroc and T. Pallidum ( syphillus)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Ox/ Diclox/nacfcillin

A
  1. second gen
  2. best against staph, only gram postive
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Ampacillin and amoxicillin

A

1.3rd gen
2.gram - and + and listeria
3.HELP - Haemophilus Ecoli Listeria Proteus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Piperacillin

A
  1. Gen 4
  2. Treats CAPES - Citrobacter, Actobacter, Psuedomonas, Serritea
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Cefazolin/Cephalexin

A
  1. 1st gen ceph
  2. treats PEK - Proteus, Ecoli , Klebsiella
  3. usually used for surgery
    4.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Cefuroxime, Cefoxitin and Cefotetan

A
  1. 2nd gen and better - converage
  2. Covers HNPEK -Haemophilus, Nesseria, Proteus, ecoli and Klebsiella

AD
Disulfram rxn

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Ceftazidime, Ceftriazone, cefotaxime

A
  1. 3rd gen more broud spectrum
  2. CAPES - Citrobacteria, Acinterbacteria, Psudomonas, Ecoli, Serratia
  3. Ceftazidime for psudomonas
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Cefepime

A
  1. 4th gen
  2. used like cefazidime
  3. IV ONLY
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Ceftaroline

A
  1. 5th gen
  2. broad + and - but cant treat psudomonas
  3. however can treat MRSA
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Cephalosporins AD

A
  1. hypersensitve
  2. GI
  3. Alchol intolerance
  4. 1st gen nephrotoxic
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Aztreonam

A
  1. MOnobactams and beta lactam sensitve
  2. only gram negative bc smol and can fit
  3. **no cross rxns ith penciliin or cephalosporins **
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What med do we use to treat someone with a gram negative bacteria who is allergic to pencillin or cephalosporins

A

Axtreonam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Meropenem

A
  1. Carbapenems
  2. treats both + and -, anerobic and Psudomonas
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Vancomycin

A
  1. Glycopetide - stops the crpss linking
  2. treat only gram positice and MRSA and Enteroccus
  3. 1st line for C. Diff but only oral
    AD
  4. Vancomycin flushing bc of histamine release
  5. Ototoxic w/ aminopsi
  6. nepho toxic
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Daptomycin

A
  1. Lipopeptides - forms pores to kill bacteria
  2. only gram + and VRE
    AD
  3. BIG MUSCLE WEAKNESS
  4. CC with the statins
  5. monitor Creatine Levels
17
Q

Gentamycin, tobramycin

A
  1. Aminoglycosides - crack membranes and bind with oxygen to get into the cell blocks 30s subunit
  2. Treatment only gram negative and pseudomonas
  3. can combo with cell wall inhibitors to attack gram positive
    AD
  4. Neph
  5. ototoxic
  6. high does muslce blocker
18
Q

Linezolid

A

1.oxlianthione - blocks mrna from the 50s subunit
2.used only gram + bc efflux on gram negative kicks it out, MRSA, eneroc
3.VRE

AD
1. GI
2. Bone marrow
3. optic
4. CAN CAUSE SEOTONIN SYNDROME

19
Q

Doxycycline and Tigecycline

A
  1. Tetracyclines binds to the 30s 2nd subunit of mRNA ribsome
  2. Docy is the 2 space 2
  3. Tigecycline is the god and hasnt been used a lot so can treat a lot of things except pseudomonas
  4. TIgecycline for VRE

AD
1.GI
2.GREY TEETH PURE CARE
3.Phototoxic

DDI
1. kids
2. pregnacny
3. Cations

20
Q

Azithromycin

A
  1. Macrolides ( the crows) blocks the 50s of translocation
    AD
  2. GI
  3. Hepatoxic
  4. QT prolonged

DDI cyp interactions except Azithromycin

21
Q

Clindamycin

A
  1. Blocks the 50s transloiation of rDNA
  2. mainly used in combo to provide coverage for anaerobes
  3. ONE OF THE BIG ANAEROBIC ABOVE DIAPHRAM
22
Q

sulfoniamides combo with trimethprim has to (BACTRIM)

A
  1. inhibits folic acid synthesis
  2. can treat MRSA
  3. usually used for UTI
  4. HPEK treats

AD
1. GI
2. Hypersensitiviry rxn
3. hemologic effects
4. Leukopenia
5. hemolytic aniema (GD6P deficentcy)
6. kernitcus - frees bullirubin and gets into our basal ganglia in neonates
7. hyperkalemia
8. block cyp
9. protein binding

Contra
1. pregnacy
2. infants

23
Q

Ciprofloxocin, Levofloxacin, moxifloxacin

A
  1. block super coiling glueing - just create strand breaks to cause cell death
  2. Cirpo can trea pseudomonas but not levo or moxi bc they made them more gram postitive
  3. made them more postice to use to treat respiroty antibitotics

AD
1. peripheral neropaty
2. photo toxic
3. seizures
4. MUSCOSKELETO - Tendonotos and tendon rupture
5. QT prolongation

CI
1. kids
2. pregnant
3. MAF Can give 2 befroe or 4 after

24
Q

Metronidazole

A
  1. produg that generates free radicals that kill anaerobic bacteria
  2. USED FOR BELOW THE DIAPGHR ANEAROBIC

AD
1. GI
2. metalic taste
3. furry tounge
4. disulfam rxn
5. no alchohol

CI
sizure
slcholism
cancer risk

25
Q

Rafampin

A
  1. Ribsome inhibitor
  2. used for TB mainly
  3. mengitis prophlaxsis
  4. hemophyllis prophlaxsis

AD
1. hepa tosic
2. red and organge body fluids
3. cyp450

26
Q

Rafampin

A
  1. Ribsome inhibitor
  2. used for TB mainly
  3. mengitis prophlaxsis
  4. hemophyllis prophlaxsis

AD
1. hepa tosic
2. red and organge body fluids
3. cyp450

MicroBio (7 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions