Antibiotics Flashcards

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1
Q

vancomycin

A

antibiotic

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2
Q

what is vanomycin’s mode of action

A

cell wall inhibitor

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3
Q

rifamycin

A

antibiotic

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4
Q

what is rifamycin’s mode of action

A

transcription inhibitor

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5
Q

tetracycline

A

antibiotic

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6
Q

what is tetracycline’s mode of action

A

protein synthesis inhibitor

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7
Q

chloramphenicol

A

antibiotic

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8
Q

what is chloramphenicol’s mode of action

A

protein synthesis inhibitor

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9
Q

clavulanic acid

A

beta-lactamase inhibitor

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10
Q

amphotericin B

A

antifungal

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11
Q

nystatin

A

antifungal

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12
Q

daunorubicin, doxorubicin, epirubicin

A

anticancer

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13
Q

bleomycin

A

anticancer

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14
Q

nocardia

A

can degrade many molecules, bioremediation applications
opportunistic pathogens causing nocardiosis

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15
Q

nocardiosis

A

usually infects the lungs, but can infect the central nervous system

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16
Q

propionibacterium

A

anaerobic or aerotolerant
found on skin and in digestive tract of animals
on human skin

17
Q

bifidobacteriales

A

anerobic
human mouth and gut microbiome

18
Q

salmonella

A

typhoid fever and gastroenteritis

19
Q

shigella

A

bacillary dysentery

20
Q

klebsiella

A

pneumonia

21
Q

yersinia

A

plague

22
Q

chlamydia

A

obligate intercellular parasites

23
Q

C. botulinum

A

ingested, botulinum toxin
food spoilage(canned)

24
Q

C. tetani

A

tetanus
produce toxins that interfere with muscle contractions
bacteria enter through open cuts on skin or wounds

25
Q

C. perfingens

A

secretes protein toxins that cause food poisoning, gas gangrene
destroys tissues, releasing proteins for fermentation
produces gas in tissues of gangrene or recent trauma
causes very painful swelling
skin turns pale to brownish red

26
Q

bacillus

A

aerobic
form endospores
antibiotics(bacitracin, polymyxin, gramicidin)

27
Q

listeria

A

L. monocytogenes cause listeriosis
infection from contaminated often ready-to-eat foods

28
Q

staphylococcae

A

faculatively anerobic, nonmotile
no endospores
common commensal of animals/humans
causal agent for many human diseases

29
Q

staphylococcus aureus

A

most important human staphylococcal pathogen
causes absecces, boils, would infections, pneumonia, toxic shock syndrome
major cause of common food poisoning
virulence factors

30
Q

virulence factors

A

coagulate which causes blood plasma to clot
toxin beta-hemolysin lyses red blood cells

31
Q

methicillin-resistant-antibiotic resistance

A

S. aureus isolates that are resistant to beta-lactam antibiotics(penicillins, and cephalosporins)
nosocomal infections(hospital)
community-associated MRSA(CA-MRSA)
appears to widely distributed in livestock population

32
Q

staphylococcus epidermidis

A

common skin resident
infections of patients with lowered resistance

33
Q

streptococcus

A

mouth, respiratory tract
species differentiation: hemolytic properties

34
Q

pyogenic streptococcus

A

sore throat, rheumatic fever, beta-hemolysis on blood agar

35
Q

oral streptococcus

A

dental caries
alpha or gamma hemolysis

36
Q

S. pneumoniae

A

lobar pneumonia and middle ear infections