Antibiotics

Question 1

antibiotics either stop the reproduction and growth of bacteria (_____) or kill the bacteria directly (_____).

Answer 1

bacteriostatic

bactericidal

Question 2

antibiotics that inhibit cell wall synthesis

1) those with a beta lactam ring
2) those without

Answer 2

1) penicillins, cephalosporins, Carbapenems e.g. meropenem

2) vancomycin, teicoplanin

Question 3

antibiotics that inhibit folic acid metabolism?

Answer 3

Sulfamethoxazole
Trimethoprim
Co-trimoxazole

Question 4

antibiotics that inhibit protein synthesis?

Answer 4

Macrolides (erythromycin, clarithromycin, azithromycin)
Clindamycin
Tetracyclines (doxycycline)
Gentamicin
Chloramphenicol

Question 5

amoxicillin coverage?

Answer 5

gram +

Question 6

co-amoxiclav coverage?

Answer 6

gram +, gram -, anaerobe

Question 7

clarithromycin coverage?

Answer 7

gram +, atypical

Question 8

clindamycin coverage?

Answer 8

gram +, anaerobe

Question 9

gentamicin coverage?

Answer 9

gram -

Question 10

ciprofloxacin coverage?

Answer 10

gram -, atypical

Question 11

metronidazole coverage?

Answer 11

anaerobe

Question 12

doxycycline coverage?

Answer 12

gram +, gram -, anaerobe, atypical

Question 13

vancomycin coverage?

Answer 13

gram +

Question 14

Start with _____ which covers streptococcus, listeria and enterococcus

Switch to ______ to additionally cover staphylococcus, haemophilus and e. coli

Switch to _____ to additionally cover pseudomonas

Switch to _____ to additionally cover ESBLs

Add _____ or _____ to cover MRSA

Add ____ or _____ to cover atypical bacteria

Answer 14

amoxicillin

co-amoxiclav

tazocin

meropenem

teicoplanin or vancomycin

clarithromycin or doxycycline