Antibioticos tumorales Flashcards

1
Q

Cual es el origen de los ATB antitumorales?

A

Origen bacteriano.

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2
Q

Cual es el mecanismo de accion de los ATB tumorales?

A

Interferir con sintesis de ADN y ARN mensajero.

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3
Q

Cuales son los ATB tumorales que vimos en clase?

A

-Bleomicina
-Actinomicina D.
-Doxorubicina
-Doxorubicina liposomica
-Daunomicina hidrocloruro
-Epirubicina
-Idarubicina.

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4
Q

Bleomicina, indicacion, reacciones adversas caracteristicas?

A

-linfoma,Ca epidermoide, Derrame malignos y Ca testicular.
-Neumonitis y Insuficiencia respiratoria.

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5
Q

Actinomicina D, indicacion y efecto adverso caracteristico?

A

-Ca testicular de Wilms
-Mielosupresion

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6
Q

Doxorubicina, indicacion efecto adverso caracteristico?

A

-Diversos tumores
-Mielosupresion/leucopenia.

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7
Q

Doxorubicina liposomica, indicacion efectos adversos importantes?

A

-Sarcoma de kaposi, ca ovario.
-Hematodepresion
-Menos toxico que la doxorubicina sola.

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8
Q

Daunomicina hidrocloruro, indicacion y efectos adversos importantes?

A

-Leucemia aguda, sarcoma de kaposi.
-Igual a la doxorubicina.

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9
Q

Epirubicina, indicacion y efectos adversos caracteristicos?

A

-Cancer de mama y gastrico
-Igual a la doxorubicina.
-

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10
Q

Idarubicina, indicacion y efectos adversos caracteristicos?

A

-LLA
- el menos cardiotoxico
-Efectos iguales de la doxorubicina.

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