Antibiotic Prescribing Flashcards

1
Q

State 3 host factors effecting antibiotic prescribing

A

Allergy
Underlying disease effecting selection/dose of antibiotic (I.e. Renal failure)
Severity of infection

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2
Q

State 2 pathogen factors effecting antibiotic prescribing

A

Common micro-organisms associated with infection site

Local susceptibility pattern

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3
Q

State 3 drug factors effecting antibiotic prescribing

A

Broad or narrow spectrum
Bactericidal or bacteriostatic
Side effects

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4
Q

Describe the mechanism of action for beta-lactam antibiotic

A

Target penicillin-binding proteins to inhibit synthesis of bacterial cell wall resulting in bactericidal

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5
Q

Name three types of beta-lactam antibiotics

A

Penicillin
Cephalosporins
Carbapenem

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6
Q

Name the 1st and 2nd line antibiotic treatment for C. diff

A

1st metrodinazole

2nd vancomycin

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7
Q

Antibiotic used in exacerbation of COPD due to infection

A

ugil

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8
Q

Antibiotic treatment for:
Mild CAP
Moderate CAP
Severe CAP

A

Mild- amoxicillin or clarithromycin
Moderate- amoxicillin + clarithromycin
Severe- co-amoxiclav/cefuroxime + clarithromycin (+ flucloxacillin if Staph. suspected)

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9
Q

1st line antibiotic treatment for pyelonephritis

A

Cefotaxime

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10
Q

1st line antibiotic treatment for lower UTI

A

Trimethoprim

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11
Q

1st line antibiotic treatment for prostatitis

A

Ciprofloxacin

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12
Q

Name the antibiotic treatment for aspiration pneumonia

A

Co-amoxiclav

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13
Q

Name the antibiotic treatment for mild HAP

A

Co-amoxiclav

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14
Q

Name the antibiotic treatment for severe HAP

A

Tazocin
+/- vancomycin for MRSA
+/- gentamicin for pseudomonas

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15
Q

Name the antibiotic treatment for GI sepsis

A

Cefuroxime + metrodinazole

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16
Q

Name the antibiotic treatment for Sepsis

A

Tazocin
+/- vancomycin if multi-resistant infection suspected
+/- gentamicin for gram-negative bacteria
(For anaerobic bacteria use cefuroxime + metrodinazole)