Antibiotic Facts

Question 1

What antibiotics work on bacterial cell wall?

Answer 1

Penicillin
Cephalosporins
Glycopeptides

Question 2

How are penicillins excreted from the body?

Answer 2

Rapidly via the kidneys

Question 3

Are penicillins safe in pregnancy?

Answer 3

Yes

Question 4

What is co-amoxiclav?

Answer 4

Combination of amoxicillin (antibiotic) and clavulanic acid (beta-lactamase inhibitor)

Question 5

How can cephalosporins be identified?

Answer 5

Any antibiotic with “cep” or “cef” in the name e.g. ceftriaxone

Question 6

Are cephalosporins broad spectrum and narrow spectrum antibiotics?

Answer 6

Broad-spectrum

Question 7

As they are broad spectrum, what is a side effect of cephalosporins?

Answer 7

Gastroenteritis secondary to a C. difficile infection

Question 8

Name 2 glycopeptides

Answer 8

Vancomycin and Teicoplanin

*Vancouver is SWEET

Question 9

How do glycopeptides work?

Answer 9

They bind to the end of the growing pentapide chain during peptidoglycan synthesis

Question 10

Are the antibiotics that act on cell wall bactericidal or bacteriostatic?

Answer 10

Bactericidal

Question 11

How are all antibiotics that work on cell wall excreted?

Answer 11

Via the kidneys and urine

*peeing on walls is fun

Question 12

Are the antibiotics that act on cell wall safe to use in pregnancy?

Answer 12

Yes

*if theres a wall, its safe

Question 13

What antibiotics inhibit protein synthesis?

Answer 13

Macrolides
Tetracyclines
Aminoglycosides
* They (dont) Make Aminos (anymore)

Question 14

Name 3 macrolides

Answer 14

Erythromycin
Clarythromycin
Azithromycin
*Everyone Adores Cake (and macrolides)

Question 15

How are macrolides excreted and what condition does this mean they are indicated for?

Answer 15

They are excreted via the liver, biliary tract and into the gut
*Pooing on lids is fun

Question 16

What is the one macrolide that is safe to use in pregnancy?

Answer 16

Erythromycin

*Only ERika can have babies

Question 17

Name an aminoglycoside

Answer 17

Gentamicin

*Dont be Gentle if you’re going be AMIN boy

Question 18

What can toxic levels of gentamicin do to the body?

Answer 18

Damage the kidneys and VIIIth cranial nerve

*Gentamicin has 10 letters (VIII + 2 kidneys)

Question 19

What antibiotics work on bacterial DNA?

Answer 19

Metronidazole
Trimethoprim (who even knows what it does?)
Fluoroquinolones

Question 20

Name 2 fluoroquinolones?

Answer 20

Ciprofloxacin and Levofloxacin

Dont Cip or Lev your toothpaste (Fluoro)

Question 21

What are the 4 C antibiotics that cause C. difficile infections?

Answer 21

Clarithromycin
Co-amoxiclav
Cephalosporins
Clindamycin