Antibiotic Facts Flashcards

1
Q

What antibiotics work on bacterial cell wall?

A

Penicillin
Cephalosporins
Glycopeptides

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2
Q

How are penicillins excreted from the body?

A

Rapidly via the kidneys

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3
Q

Are penicillins safe in pregnancy?

A

Yes

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4
Q

What is co-amoxiclav?

A

Combination of amoxicillin (antibiotic) and clavulanic acid (beta-lactamase inhibitor)

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5
Q

How can cephalosporins be identified?

A

Any antibiotic with “cep” or “cef” in the name e.g. ceftriaxone

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6
Q

Are cephalosporins broad spectrum and narrow spectrum antibiotics?

A

Broad-spectrum

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7
Q

As they are broad spectrum, what is a side effect of cephalosporins?

A

Gastroenteritis secondary to a C. difficile infection

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8
Q

Name 2 glycopeptides

A

Vancomycin and Teicoplanin

*Vancouver is SWEET

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9
Q

How do glycopeptides work?

A

They bind to the end of the growing pentapide chain during peptidoglycan synthesis

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10
Q

Are the antibiotics that act on cell wall bactericidal or bacteriostatic?

A

Bactericidal

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11
Q

How are all antibiotics that work on cell wall excreted?

A

Via the kidneys and urine

*peeing on walls is fun

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12
Q

Are the antibiotics that act on cell wall safe to use in pregnancy?

A

Yes

*if theres a wall, its safe

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13
Q

What antibiotics inhibit protein synthesis?

A

Macrolides
Tetracyclines
Aminoglycosides
* They (dont) Make Aminos (anymore)

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14
Q

Name 3 macrolides

A

Erythromycin
Clarythromycin
Azithromycin
*Everyone Adores Cake (and macrolides)

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15
Q

How are macrolides excreted and what condition does this mean they are indicated for?

A

They are excreted via the liver, biliary tract and into the gut
*Pooing on lids is fun

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16
Q

What is the one macrolide that is safe to use in pregnancy?

A

Erythromycin

*Only ERika can have babies

17
Q

Name an aminoglycoside

A

Gentamicin

*Dont be Gentle if you’re going be AMIN boy

18
Q

What can toxic levels of gentamicin do to the body?

A

Damage the kidneys and VIIIth cranial nerve

*Gentamicin has 10 letters (VIII + 2 kidneys)

19
Q

What antibiotics work on bacterial DNA?

A

Metronidazole
Trimethoprim (who even knows what it does?)
Fluoroquinolones

20
Q

Name 2 fluoroquinolones?

A

Ciprofloxacin and Levofloxacin

Dont Cip or Lev your toothpaste (Fluoro)

21
Q

What are the 4 C antibiotics that cause C. difficile infections?

A

Clarithromycin
Co-amoxiclav
Cephalosporins
Clindamycin