Antibiotic Drugs Flashcards
What are the 5 mechanisms of Antibacterial actions?
- Inhibition of bacterial cell-wall synthesis
- Alteration of membrane permeability
- Inhibition of protein synthesis
- Inhibitions of the synthesis of bacterial RNA and DNA
- Interference with metabolism within the cell
What are the 3 general adverse reaction to Antibacterial drugs?
- Allergy or Hypersensitivity
- Superinfection
- Organ toxicity
It occurs when one antibiotic increases the effectiveness of the 2nd drug.
Potentiative Effect
What drug destroy the bacteria by altering their DNA, does not affect the human DNA, it is suitable for treating complicated UTI’s and can be given to patients with GIT, respiratory, skin and bone infections?
Quinolones
What drug inhibit the bacterial growth by preventing synthesis of folic acid?
Trimethoprim-sulfamethoxazole
What are the 2 Tuberculosis injections?
Purified protein derivative (PPD)
Bacille Calmette-Guerin
What drug prevents the synthesis of glucans which are found in fungal cell walls?
Echinocandins
A term used to describe Fungal infection.
Mycosis
What kind of disease can be transmitted through blood transfusions, mother to child, or through use of contaminated needles?
Malaria
What are the 3 medicines can be used for severe malaria?
Artesunate IV
Primaquine
Quinine
What drug have a mechanism of action that interferes with DNA, resulting inhibition of protein synthesis and cell death in susceptible organisms?
Metronidazole
What non-malarial antiprotozoals drug used in caution in patients with CNS, hepatic disease and lactating women?
Metronidazole
A drug that destroyed worm’s cytoplasm which immobilizes and kills the worm.
Albendazole
What stage of HIV infection have a severe symptom that can lead to death?
Stage 4
What are the goals of the Highly Active Antiretroviral Therapy (HAART)?
1.Decrease viral load to undetectable levels.
2.Preserve and increase number of CD4+T cells.
3.Prevent resistance.
4.Have client in good clinical condition.
5.Prevent secondary infections and cancers.
