antibiotic classes and their actions Flashcards

1
Q

Beta- lactams

A

inhibition of cell wall synthesis

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2
Q

aminoglycosides and tetracyclines

A

inhibit protein synthesis by binding to 30S ribosomal subunit

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3
Q

chloramphenicol and Macrolide-lincosamide group

A

inhibit protein synthesis by binding to 50S ribosomal subunit

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4
Q

fluoroquinolones

A

inhibit DNA synthesis by binding GNA gyrases

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5
Q

rifampin

A

inhibits RNA synthesis by binding DNA- dependent , RNA polymerase

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6
Q

sulfonamides

A

folic acid pathway inhibition (binds with dihydropteroate synthase)

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7
Q

trimethoprim

A

folic acid pathway inhibition (binds with dihydrofolate reductase)

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8
Q

metronidazole

A

disruption of DNA

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9
Q

polymyxins

A

disruption of cell membrane

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