Antibiotic Classes Flashcards

Have an understanding of which antibiotics are in each class, their mechanism of action and their coverage.

1
Q

Name the penicillin antibiotics

A
Penicillin
Flucloxacillin
Amoxicillin
Piperacillin/tazobactam
Co-amoxiclav
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2
Q

Are penicillins bacteriostatic or bactericidal?

A

Bactericidal

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3
Q

How to penicillins work?

A

Inhibiting cell wall synthesis

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4
Q

What does piperacillin/tazobactam not cover?

A

Pseudomonas and very resistant coliforms

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5
Q

What does co-amoxiclav not cover?

A

Pseudomonas and MRSA

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6
Q

Name the antibiotics in the carbapenem class

A

Meropenem

Imipenem

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7
Q

Are carbapenems bacteriostatic or bactericidal?

A

Bactericidal

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8
Q

Name the cephalosporin antibiotics

A

Cephalexin
Ceftriaxone
Aztreonam

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9
Q

Are cephalosporins bacteriostatic or bactericidal?

A

Bactericidal

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10
Q

How do cephalosporins work?

A

Prevent peptidoglycan cross-linking

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11
Q

Is clindamycin bacteriostatic or bactericidal?

A

Bacteriostatic

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12
Q

How does clindamycin work?

A

Inhibits protein synthesis

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13
Q

Name the quinolone antibiotics

A

Ofloxacin
Ciprofloxacin
Levofloxacin

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14
Q

Are quinolones bacteriostatic or bactericidal?

A

Bactericidal

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15
Q

How do quinolones work?

A

Interact with enzymes that coil and uncoil DNA

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16
Q

Name the glycopeptide antibiotics

A

Vancomycin

Teicoplanin

17
Q

Name the tetracycline antibiotics

A

Doxycycline

18
Q

Are glycopeptides bacteriostatic or bactericidal?

A

Bactericidal

19
Q

How do glycopeptides work?

A

Binds to end of growing peptide chain

20
Q

Are tetracyclines bacteriostatic or bactericidal?

A

Bacteriostatic

21
Q

How do tetracyclines work?

A

Inhibit protein synthesis

22
Q

Name the macrolide antibiotics

A

Erythromycin
Clarithromycin
Azithromycin

23
Q

Are macrolides bacteriostatic or bactericidal?

A

Bacteriostatic

24
Q

How do macrolides work?

A

Inhibit protein synthesis

25
Name the aminoglycoside antibiotics
Gentamicin Amikacin Tobramycin
26
Are aminoglycosides bacteriostatic or bactericidal?
Bactericidal
27
How do aminoglycosides work?
Inhibit protein synthesis
28
Is chloramphenicol bacteriostatic or bactericidal?
Bacteriostatic
29
How does chloramphenicol work?
Inhibit protein synthesis
30
Name the nitromanidazole antibiotics?
Metronidazole
31
Is metronidazole bacteriostatic or bactericidal?
Bactericidal
32
How does metronidazole work?
Acts on bacterial DNA
33
What does co-trimoxazole consist of?
Trimethoprim: pyrimidine inhibitor of dihydrofolate reductase AND Sulfamethoxazole: sulfonamide
34
Are sulphonamides bacteriocidal or bacteriostatic?
Bacteriostatic
35
Is co-trimazole bacteriostatic or bactericidal?
Bactericidal
36
Is polymixin bacteriostatic or bactericidal?
Bactericidal
37
Which antibiotics are B-lactams?
Penicillin's Carbapenems Cephalosporins