Antibiotic Classes Flashcards
Have an understanding of which antibiotics are in each class, their mechanism of action and their coverage.
Name the penicillin antibiotics
Penicillin Flucloxacillin Amoxicillin Piperacillin/tazobactam Co-amoxiclav
Are penicillins bacteriostatic or bactericidal?
Bactericidal
How to penicillins work?
Inhibiting cell wall synthesis
What does piperacillin/tazobactam not cover?
Pseudomonas and very resistant coliforms
What does co-amoxiclav not cover?
Pseudomonas and MRSA
Name the antibiotics in the carbapenem class
Meropenem
Imipenem
Are carbapenems bacteriostatic or bactericidal?
Bactericidal
Name the cephalosporin antibiotics
Cephalexin
Ceftriaxone
Aztreonam
Are cephalosporins bacteriostatic or bactericidal?
Bactericidal
How do cephalosporins work?
Prevent peptidoglycan cross-linking
Is clindamycin bacteriostatic or bactericidal?
Bacteriostatic
How does clindamycin work?
Inhibits protein synthesis
Name the quinolone antibiotics
Ofloxacin
Ciprofloxacin
Levofloxacin
Are quinolones bacteriostatic or bactericidal?
Bactericidal
How do quinolones work?
Interact with enzymes that coil and uncoil DNA
Name the glycopeptide antibiotics
Vancomycin
Teicoplanin
Name the tetracycline antibiotics
Doxycycline
Are glycopeptides bacteriostatic or bactericidal?
Bactericidal
How do glycopeptides work?
Binds to end of growing peptide chain
Are tetracyclines bacteriostatic or bactericidal?
Bacteriostatic
How do tetracyclines work?
Inhibit protein synthesis
Name the macrolide antibiotics
Erythromycin
Clarithromycin
Azithromycin
Are macrolides bacteriostatic or bactericidal?
Bacteriostatic
How do macrolides work?
Inhibit protein synthesis
Name the aminoglycoside antibiotics
Gentamicin
Amikacin
Tobramycin
Are aminoglycosides bacteriostatic or bactericidal?
Bactericidal
How do aminoglycosides work?
Inhibit protein synthesis
Is chloramphenicol bacteriostatic or bactericidal?
Bacteriostatic
How does chloramphenicol work?
Inhibit protein synthesis
Name the nitromanidazole antibiotics?
Metronidazole
Is metronidazole bacteriostatic or bactericidal?
Bactericidal
How does metronidazole work?
Acts on bacterial DNA
What does co-trimoxazole consist of?
Trimethoprim: pyrimidine inhibitor of dihydrofolate reductase
AND
Sulfamethoxazole: sulfonamide
Are sulphonamides bacteriocidal or bacteriostatic?
Bacteriostatic
Is co-trimazole bacteriostatic or bactericidal?
Bactericidal
Is polymixin bacteriostatic or bactericidal?
Bactericidal
Which antibiotics are B-lactams?
Penicillin’s
Carbapenems
Cephalosporins