Antibiotic: Bone and Joint Flashcards
1
Q
Discitis/ Vertebral Osteomyelitis
A
- vancomycin PLUS
- cefepime / ciprofloxacin
Requires culture of bone/blood/disc to ID cause. can withold empiric Abx to definitive treatment. High risk pt = IV drug use, endocarditis, neurologic deficits.
2
Q
Infectious Tenosynovitis
A
- vancomycin PLUS
- ceftriaxone/ levofloxacin
3
Q
Adult bite wound
A
- ampicillin/sulbactam.
- ceftriaxone IV AND metronidazole IV
- levofloxacin IV AND metronidazole IV
- vancomycin is MRSA (+).
4
Q
Pediatric Bite Wound
A
- ampicillin/sulbactam
- ceftriaxone IV And metronidazole IV
- clindamycin AND bactrim
- vancomycin is MRSA(+) in addition to one of above.
5
Q
Water related soft tissue infections
A
- Mycobacteria
- clarithromycin PLUS
- ethambutol OR rifampin
- clarithromycin PLUS
- Psuedomonas
- levofloxacin
6
Q
Disseminated gonococcal infection with Chlamydial coverage
A
- ceftriaxone IV PLUS
- azithromycin OR
- doxycycline
7
Q
Open Fractures
A
- Type I / II
- cefazolin IV.
- PCN allergy: vancomycin
- Type III
- gentamicin PLUS one abx from step 1.
pip/tazo if concerned for clostridia from soil contamination.
Type I: open fracture with < 1 cm clean lac.
Type II: Open Fx > 1cm lac.
Type III: open Fx with extensive soft tissue damage
8
Q
Osteomyelitis
A
- vancomycin PLUS
- ceftriaxone
- (+/-) pseudomonas: cefepime OR ciprofloxacin in place of ceftriaxone.
- Associated pediatric sickle cell
- ceftriaxone PLUS vancomycin
9
Q
Non-gonococcal Septic Arthritis
A
- vancomycin PLUS
- ceftriaxone OR
- cefepime OR
- ciprofloxacin
10
Q
Gonococcal septic arthritis
A
Ceftriaxone
11
Q
Sickle cell and Septic Arthritis
A
- Vancomycin PLUS
- ciprofloxacin OR
- Imipenem/cilastin
12
Q
Septic Bursitis Oupatient
A
- bactrim
- clindamycin
2-3wk course.
13
Q
Septic Bursitis inpatient
A
- vancomycin
- linezolid
- clindamycin
