Antibiotic Action Flashcards

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1
Q

Which antibiotics inhibit nucleic acid synthesis via inhibiting folate synthesis

A

Trimethoprim
Sulphonamides
Sulphamethoxazole

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2
Q

Which antibiotics inhibit nucleic acid synthesis via inhibiting DNA gyrase

A

Fluroquinolones
Ciprofloxacin

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3
Q

Which antibiotic inhibit nucleic acid synthesis via binding to RNA polymerase

A

Rifampicin

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4
Q

Which antibiotic inhibit nucleic acid synthesis via breaking DNA strand

A

Metronidazole

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5
Q

Which antibiotics inhibit cell wall synthesis

A

Glycopeptides (Vancomycin, Teicoplanin)
Beta lactams
- Penicillin’s (Benzylpenecillin, Amoxicillin, Flucloxacillin)
- Cephalosporin’s (Cephalexin, Cefotaxime, Ceftriaxone)
- Carbapenams (Imipenem, Estapenem)

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6
Q

Which antibiotics inhibit protein synthesis

A

Chloramphenicol
Macrolides
- Clarithromycin
- Erythromycin
Tetracycline’s
- Doxycycline
Aminogylcosides
- Gentamycin
- Streptomycin

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7
Q

Which antibiotic is usually used when a patient has penicillin allergy

A

Macrolides

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8
Q

What is used to treat MRSA infections

A

Aminoglycoside - Vancomycin

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9
Q

Antibiotic sensitivity testing

A

Mueller-hinton agar
Allows standardised diffusion rate of antibiotics away from the disc + throughout the agar
Reliable + Repeatable

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