Antibiotcs Flashcards
1
Q
Fluoroquinolone MOA
A
Inhibition of DNA gyrase (topoisomerase II)
required for bacterial DNA replication, transcription, repair and recombination
2
Q
Penicillin G
A
Beta-lactam
3
Q
Penicillin G spectrum
A
Gram +
Not Staphylococcus spp
Anaerobes
Not Bacteriodes spp
4
Q
Penicillin G pharmacokinetics
A
Time-dependent
Cidal
Water soluble - distributed via ECF
5
Q
Penicillin G MOA
A
Irreversibly binds PBD - intervening with cell wall peptidoglycans - cell lysis