Antibiotcs Flashcards

1
Q

Fluoroquinolone MOA

A

Inhibition of DNA gyrase (topoisomerase II)
required for bacterial DNA replication, transcription, repair and recombination

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2
Q

Penicillin G

A

Beta-lactam

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3
Q

Penicillin G spectrum

A

Gram +
Not Staphylococcus spp
Anaerobes
Not Bacteriodes spp

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4
Q

Penicillin G pharmacokinetics

A

Time-dependent
Cidal
Water soluble - distributed via ECF

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5
Q

Penicillin G MOA

A

Irreversibly binds PBD - intervening with cell wall peptidoglycans - cell lysis

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