ACVIM Consensus 2014-2019 Flashcards
Strangles - year and first author
- Boyle
Reportable in USA
2017
Streptococcus Equi subs Equi clinical signs
Young > old.
Fever develops 3-14 days post exposure.
Pharyngitis - submandibular and retropharyngeal lymph node abscessation.
Horses with strangles are at risk of
Respiratory distress
Neuropraxia
Recurrent laryngeal nerve damage
“Bastard strangles”
Pneumonia
Pathogenesis
Mouth/nose - crypts of lingual and palatine tonsils - follicular associated epithelium of the pharyngeal and tubal tonsils - translocation - mandibular and retropharyngeal lymph nodes
Strep Equi pathogenesis
Avoids neutrophil phagocytosis: hyaluronic acid capsule, anti-phagocytic SeM protein, H-factor binding Se 18.9, Mac protein and other.
How to dispose of Strep equi bacteria
Lance the abscess capsule and clean.
When does nasal shedding start and stop
Start 2-3 days post-pyrexia.
2-3 weeks duration.
Immunity and reinfection
Without antibiotics - 75% develop long term immunity.
20 - 25% susceptible to reinfection within months.
Control
- Shedding 1-2 days post-pyrexia: ISOLATE WHEN PYREXIC
- Nasal shedding 2-3 weeks.
- Infectious app 6 weeks after purulent discharge stopped
- Persistent guttural infection - intermittent shedding for years