Antibacterials Flashcards

1
Q

What is the MOA for Folate Antagonist drugs: Sulfonamides?

A

Inhibitor of folate production

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2
Q

What is the MOA for Folate Antagonist drugs:

Sulfone?

A

Competitive antagonist of PABA which prevents bacterial folate synthesis

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3
Q

What drugs are Folate Antagonist drugs:

Sulfonamides?

A

TMP – SMZ
[Bactrim]
[Septra]

Trimethoprim-Sulfamethoxazole
&
Sulfisoxazole
[Gantrisin]

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4
Q

What drug is a Folate Antagonist:

Sulfone?

A

Dapsone

[Aczone 5% Gel]

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5
Q

What is the MOA for Flouroquinolone?

A

DNA gyrase inhibitor

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6
Q

What drugs are Flouroquinolone?

A

Ciprofloxacin [Cipro],
Levofloxacin [Levaquin],
Moxifloxacin {Avelox}

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7
Q

TMP – SMZ
[Bactrim]
[Septra]
Trimethoprim-Sulfamethoxazole

A

Folate Antagonist:
Sulfonamides.
Inhibitor of folate production

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8
Q

Sulfisoxazole

[Gantrisin]

A

Folate Antagonist:
Sulfonamides.
Inhibitor of folate production

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9
Q

Dapsone

[Aczone 5% Gel]

A

Folate Antagonist:
Sulfone.
Competitive antagonist of PABA which prevents bacterial folate synthesis

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10
Q

Ciprofloxacin [Cipro]

A

Flouroquinolone.

DNA gyrase inhibitor

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11
Q

Levofloxacin [Levaquin],

A

Flouroquinolone.

DNA gyrase inhibitor

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12
Q

Moxifloxacin {Avelox}

A

Flouroquinolone.

DNA gyrase inhibitor

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