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Pharm I > Antiarrhythmics > Flashcards

Antiarrhythmics Flashcards

1
Q

quinidine

A

Class: IA
MOA: (Na+) channel blockers (intermediate); K+ channel blocking effect
Indications: ventricular arrhythmias; paroxysmal recurrent afib
Long QT

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2
Q

procainamide

A

Class IA
MOA: Na channel block(intermediate); K channel block
Indications: ventricular arrhythmias; paroxysmal recurrent afib; WPW
Long QT

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3
Q

dispyramide

A

Class IA
MOA: Na channel blocker(intermediate), K channel blocker
Indications: Ventricular arrhythmias; recurrent paroxysmal afib
Long QT

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4
Q

lidocaine

A

Class IB
MOA: Na channel blocker(fast association/disassociation)
Indications: Vtach

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5
Q

mexilitene

A

Class IB
MOANa channel blockers (fast association/disassociation)
Indicated: Vtach

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6
Q

Flecainide

A

Class IC
MOA: Na channel blocker (slow association/disassociation)
indicated: paroxysmal afib; recurrent tachycardias of abnormal conduction
*contrindicated s/p MI

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7
Q

propafenone

A

Class IC
MOA: Na channel blocker (slow association/disassociation)
indicated: paroxysmal afib; recurrent tachycardias of abnormal conduction
*contrindicated s/p MI

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8
Q

sotalol

A

Class III
MOA: K channel blocker
Indications: WPW; Vtach; afib

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9
Q

dofetilide

A

Class III
MOA: K channel blocker
Indications: WPW;

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10
Q

amiodarone

A

Class III
MOA: K channel blocker
Indications: WPW;

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11
Q

dronedarone

A

Class III
MOA: K channel blocker
Indications: WPW;

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12
Q

ibutilide

A

Class III
MOA: K channel blocker
Indications: WPW; afib, aFlutter

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13
Q

adenosine

A

Class V
MOA
Indications: SVTs

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14
Q

diltiazem

A

Class IV
MOA: Ca channel blocker
Indications: paroxysmal SVT; reduce ventricular rate in afib

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15
Q

Verapamil

A

Class IV
MOA: Ca channel blocker
Indications: paroxysmal SVT; reduce ventricular rate in afib

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16
Q

Digoxin

A

Class V
MOA: Na/K atpase=> increased intracellular (Na)=> reverses Na-Ca exchanger => increased intracellular Ca=> increased contractility
Indications: afib, aflutter, HF

17
Q

Magnesium Sulfate

A

Class V
MOA:
Indications: Torsades de pointe; quinidine induced arrhythmias

Pharm I (8 decks)

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