Antiarrhythmics

Question 1

Class IA (MOA), Drugs

Answer 1

Sodium channel blocker

Depress phase 0, prolong action potenial duration

Disopyramide

Question 2

Class IB (MOA), Drugs

Answer 2

Sodium channel blocker

Depress phase 0, shorten action potential duration

Mexiletine

Question 3

Class IC (MOA), Drugs

Answer 3

Sodium channel blocker

Depress phase 0, slowing of conduction

Flecainide
Propafenone

Question 4

Class II (MOA), Drugs

Answer 4

Beta blocker

Depress phase 4 depolarization

Propranolol

Question 5

Class III (MOA), Drugs

Answer 5

Produce a prolongation of phase 3 (repolarization)

Amiodarone
Dronedarone
Sotalol

Question 6

Class IV (MOA), Drugs

Answer 6

Calcium channel blocker

Depress phase 4 depolarization and lengthen phase 1 and 2 of repolarization

Diltiazem
Verpamil

Question 7

Disopyramide (class)

Answer 7

Class IA antiarrhythmic, sodium channel blocker

Question 8

Flecainide (class)

Answer 8

Class 1C antiarrythmic, sodium channel blocker

Question 8

Mexiletine (class)

Answer 8

Class 1B antiarrythmic, sodium channel blocker

Question 9

Propafenone (class)

Answer 9

Class 1C antiarrythmic, sodium channel blocker

Question 10

Propranolol (class)

Answer 10

Class II antiarrythmic, beta blocker (non-selective)

Question 11

Amiodarone (class)

Answer 11

Class III antiarrythmic

Question 12

Dronedarone (class)

Answer 12

Class III antiarrythmic

Question 13

Sotalol (class)

Answer 13

Class III antiarrythmic

Question 14

Diltiazem (class)

Answer 14

Class IV antiarrythmic, calcium channel blocker

Question 15

Verapamil (class)

Answer 15

Class IV antiarrythmic, calcium channel blocker