Antiarrhythmic drugs for Tachy- and Bradyarrhythmias Flashcards
Class IA
Prolongs action potential
Quinidine
Procainamide
Disopyramide
Class IB
Shortens action potential Lidocaine Phenytoin Tocainide Mexiletine Aprinidine
Class IC
No effect on action potential
Flecainide
Encainide
Lorcainide
Class II
Beta blockers Propanolol Timolol Pinololol Oxyprenolol Alprenolol Atenolol Esmolol Metoprolol
Class III
Potassium channel blockers
Bretylium
Amiodarone
Sotalol (nonselective Beta blocker)
Class IV
Calcium channel blockers
Verapamil
Diltiazem
Therapeutic uses of Quinidine
Ventricular arrhythmias
Atrial fibrillation in horses (drug of choice), cattle, and large breed dogs
Therapeutic use of Procainamide
More effective for ventricular arrhythmias than atrial arrhythmias
Therapeutic uses of Lidocaine
The intravenous drug of choice for ventricular arrhythmias due to general anesthetics, surgery, ischemia, and trauma
Digitalis-induced arrhythmias
Therapeutic uses of Phenytoin
Digitalis-induced arrhythmias in dogs only
Therapeutic uses of Propanolol
Paroxysmal supraventricular tachycardia
Digitalis-induced tachyarrhythmias
Arrhythmias due to inhalation anesthesia
Therapeutic use of Bretylium
Refractory and recurrent tachyarrhythmias
Therapeutic uses of Verapamil and Diltiazem
Supraventricular tachyarrhythmias
Myocardial hypertropy
Supraventricular tachyarrhythmias in dogs
-Atrial tachycardia treatment
Digoxin
Procainamide, propanolol
Quinidine, phenytoin
Supraventricular tachyarrhythmias in dogs
-Atrial flutter
Digoxin
Quinidine, procainamide, propanolol