Antianginal Drugs

Question 1

it is an inhaled drug that is very short acting but it is not popular due to its bad odor

Answer 1

amyl nitrate

Question 2

short acting and fast onset drugs

Answer 2

amyl nitrate, nitroglycerin (sublingual and intravenous)

Question 3

mainstay of antianginal treatment; can be taken sublingually at home, or intravenously in the hospital, both are very short acting

Answer 3

nitroglycerin (sublingual and intravenous)

Question 4

long acting organic nitrites and nitrates?

Answer 4

Nitroglycerin (Buccal Trans-mucosal), Nitroglycerin (Oral), Nitroglycerin (transdermal)
Isosorbide dinitrate(sublingual), isosorbide dinitrate (Oral), isosorbide mononitrate(Oral), Erithrityl tetra-nitrate (Sublingual), Erithrityl tetra-nitrate (oral), Penta-erythritol tetra-nitrate (PETN)

Question 5

out of the long acting nitroglycerin, which one has the fastest onset of action

Answer 5

Nitroglycerin (Buccal Trans-mucosal)

Question 6

PETN is special in that it is

Answer 6

explosive

Question 7

is taken in the cheek, it is fast onset but can last for several hours

Answer 7

buccal nitroglycerin

Question 8

has slower onset but is longer lasting than the IV, buccal, or sublingual formulations

Answer 8

oral nitroglycerine

Question 9

good for patients with nocturnal angina

Answer 9

transdermal nitroglycerin

Question 10

popular for angina pectoris

Answer 10

nitrates and nitrites

Question 11

Erithrityl tetranitrate comes in how many forms

Answer 11

sublingual and oral forms

Question 12

Pentaerythritol Tetra-nitrate comes in what form

Answer 12

oral form

Question 13

isosorbide comes in what forms

Answer 13

isosorbide dinitrate comes in sublingual and oral forms and isosorbide mono-nitrate comes only in oral form. both are slow onset and long acting

Question 14

adsorbed on lactose, colloidal silicone dioxide and silicone medical fluid

Answer 14

transdermal nitroglycerin

Question 15

a layer of what ensures the attachment of transdermal nitroglycerin to skin

Answer 15

a layer of silicone adhesive

Question 16

non selective beta 1 and 2 adrenergic receptor blockers first generation

Answer 16

nadolol and propranolol

Question 17

membrane stabilizing property, which is essentially a sodium channel blocking affect which makes it effective as an antiarrhythmic

Answer 17

propranolol, metoprolol

Question 18

long acting first generation non selective beta blocker

Answer 18

nadolol

Question 19

non selective B- adrenergic receptor blockers are not useful for

Answer 19

these drugs are not useful in the treatment of prinzmetal’s angina because of the possible constriction of coronary arteries due to un-opposed effect of alpha-1 adrenergic receptor activation; nadolol and propranolol

Question 20

have a profound effect on vasodilation, and are useful for angina. They have no effect on AV node conduction, and are not useful as antiarrhythmics

Answer 20

nifedipine and amlodipine

Question 21

have an affect on vasodilation, as well as controlling AV node conduction. Therefore they are good for angina, as well as arrhythmia

Answer 21

diltiazem and verapamil