Antianginal Drugs Flashcards
atherosclerosis
a common form of arteriosclerosis involving deposits of fatty, cholesterol-containing material (plaques) within the arterial walls
angina pectoris
chest pain that occurs when the heart’s supply of blood carrying oxygen insufficient to meet the demands of the heart
chronic stable angina
chest pain that is primarily caused by atherosclerosis, which results in a long-term but relatively stable level of obstruction in one or more coronary arteries
coronary arteries
arteries that deliver oxygen to the heart muscle
coronary artery disease (CAD)
any one of the abnormal conditions that can affect the arteries of the heart and produce various pathologic effects, especially a reduced supply of oxygen and nutrients to the myocardium
ischaemia
poor blood supply to an organ
ischaemia heart disease
poor blood supply to the heart via the coronary arteries
myocardial infarction (MI)
necrosis of the myocardium following interruption of blood supply; it is almost always caused by atherosclerosis of the coronary arteries and is commonly called a heart attack
reflex tachycardia
a rapid heartbeat caused by a variety of autonomic nervous system effects, such as blood pressure changes, fever, or emotional stress
unstable angina
early stage of progressive coronary artery disease
vasospastic angina
ischaemia-induced myocardial chest pain caused by spasms of the coronary arteries; also referred to as Prinzmetal or variant angina
beta bloomers adverse affects: cardiovascular system
bradycardia, hypotension, atrioventricular block
beta blockers adverse affects: central nervous system
dizziness, fatigue, depression, lethargy
beta blockers adverse affects: metabolic
hyperglycaemia and/or hypoglycaemia, hyperlipidaemia
beta blockers adverse affects: other
wheezing, dyspnea, impotence
calcium channel blockers: benzothiazepines
diltiazem [Cardizem, Dilacor, Tiazac, Dilacor XR, Cartia XT, Matzim LA, Taztia XT, Diltia XT
calcium channel blockers: dihydropyridines
amlodopine [Norvasc], felodipine [Plendil], isradipine [DynaCirc], nicardipine [Cardene], nifedipine [Adalat, Procardia], nimodipine [Nimotop]
calcium channel blockers: phenylalkylamines
verapamil [Calan, Isoptin, Verelan
calcium channel blockers adverse effects: cardiovascular system
hypotension, palpitations, tachycardia or bradycardia
calcium channel blockers adverse effects: gastrointestinal
constipation, nausea
calcium channel blockers adverse effects: other
dyspnea, rash, flushing, peripheral oedema
antianginal drugs
amlodipine, atenolol, diltiazem, isosorbide dinitrate, isosorbide mononitrate, metoprolol, nitroglycerin, ranolazine
angina pectoris
chest pain that occurs when the heart’s supply of blood carrying oxygen insufficient to meet the demands of the heart
atherosclerosis
a common form of arteriosclerosis involving deposits of fatty, cholesterol-containing material (plaques) within the arterial walls
