ANTI-VIRAL DRUGS Flashcards

1
Q

three classes that treat HIV

A
  1. NRTI’s
  2. NNRTI’s
  3. Protease Inhibitors
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2
Q

NRTI drug (1)

A

emtricitabine

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3
Q

NNRTI drug (1)

A

efavirenz

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4
Q

Protease Inhibitor drug (1)

A

nitonavir

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5
Q

emtricitabine BB

A

lactic acidosis, severe hepatomegaly

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6
Q

efavirenz BB

A

teratogenic

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7
Q

nitonavir BB

A

CYP3A4 INHIBITOR (cadmic with hypnotics, anti-arrythmics, and ergot derivatives)

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8
Q

5 classes that treat HCV

A
  1. long acting interferons
  2. NS3/4A inhibitor
  3. Ribavirin
  4. NS5A inhibitor
  5. NS5B inhibitor
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9
Q

long acting interferon drugs (2)

A

peginteferon alpha 2 a and b

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10
Q

NS3/4A inhibitor drug (1)

A

paritaprevir

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11
Q

NS5A inhibitor drug (1)

A

ledipAsvir

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12
Q

NS5B inhibitor drug (1)

A

sofosBuvir

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13
Q

class that treats influenza

A

neuroamindase inhibitor

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14
Q

neuroamindase inhibitor drug (1)

A

oseltamvir

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15
Q

drug that treats HSV/VZV

A

valacyclovir

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16
Q

drug that treats TB

A

pyrazinomide

17
Q

drug that treats peripheral neuropathy that is an AE of TB tx

A

pyridoxine

18
Q

peginterferon BB

A

can cause/aggravate autoimmune, infection, and CVA

19
Q

1st line tx of HCV

A

NS5A and B - ledipAsvir and sofosBuvir

20
Q

which is the only HCV drug that can be given as monotherapy

A

long acting interferons (SQ)