Anti-psychotics Flashcards
chlorpromazine
1st generation dopamine D2 receptor antagonist
dopamine systems (4)
mesolimbic, mesocortical, nigrastriatal, tuberoinfundibular
halperidol
1st generation dopamine D2 receptor antagonist; side fx: mov’t disorder
clozapine
2nd generation (lower affinity) dopamine D2 receptor antagonist; most effective anti-psychotic; side fx: agranulocytosis, myocarditis
risperidone
2nd generation (lower affinity, intermittent activation) dopamine D2 receptor antagonist; side fx: CVD, hyperlipidemia, hyperglycemia
quetiapine
2nd generation (lower affinity, intermittent activation) dopamine D2 receptor antagonist; side fx: CVD, hyperlipidemia, hyperglycemia
olanzapine
2nd generation (lower affinity, intermittent activation) dopamine D2 receptor antagonist; side fx: CVD, hyperlipidemia, hyperglycemia
aripiprazole
2nd generation, dopamine D2 receptor partial agonist