Anti-psychotic Drugs Flashcards
Antipsychotic medication is given to patient with?
Patient with altered sense of reality
2 Types of classification for antipsychotic medication
Typical
Atypical
2 types of classification for Typical medications
Phenothiazine
Non-phenothiazine
Antipsychotic drugs indicated for schizophrenia
Phenothiazine
Positive s/s of schizophrenia
Hallucination
Delusion
Disorganized thinking (neologism, echolalia, flight of ideas)
Disorganized behavior (agitation, aggression,echopraxia, regressed childlike behavior)
Echopraxia - imitation of another gestures
Negative signs of schizophrenia
Mute, flat affect, catatonic, suicidal, homicidal
Example of Phenothiazine
“Remember No Cee,Pee,Triflou,Theori”
Chlorpromazine
Perphenazine
Triflouperazine
Thioridazine
“ Ends in ZINE”
Ideal route for Phenothiazine
IM
“ other PO, IV”
Side effects of Phenothiazine
Anticholinergic +
Tardive dyskinesia
Form of movement that is drug induced, toungue potruding, rocking back and forth
Tardive dyskinesia
“Extrapyramidal effect”
Nursing assessment when giving phenothiazine, monitor for:
Tardive dyskinesia
Specific v/s to monitor for phenothiazine
Increase in temperature
Orthostatic hypotension
Position after administration of phenothiazine
Lay flat for 1 hr
How many weeks for phenothiazine to work?
2 weeks
Example of non-phenothiazine
Haloperidol
Side effects of Haloperidol
Anticholinergic +
Severe tardive dyskinesia
Severe EPS
Antidote for antipsychotic drugs
Benztropine
“Parkinson’s drug”
Teaching points regarding the side effects of antipsychotic drugs. Do you need to report to HCP?
No,Side effects are normal and expected
Continue taking the drugs or the psychotic symptoms will return
What is the adverse reaction to antipsychotic drug? Medical emergency
Neuroleptic malignant syndrome (NMS)
S/S of NMS
Anticholinergic +
Tardive dyskinesia +
Extreme vital signs ( increase HR, RR, T, rigid body, sweating, seizure)
Immediate nursing action for NMS
Notify HCP
Stop the meds
Provide supportive care ( acetaminophen and cooling blanket for increase temperature, beta-blocker to decrease BP, IVF)
Antipsychotic drug classification, used to treat psychotic symptoms but newer medication
Atypical antipsychotic
Examples of Atypical antipsychotic drugs
“Remember CORA”
Clozapine
Olanzapine
Risperodone
Aripiprazole
“Less EPS symptoms”
What to monitor for patients taking atypical antipsychotic drugs?
Metabolic changes
What are those metabolic changes for taking atypical drugs?
Obesity
DM
Hyperlipidemia - inc. cholesterol 200mg/dl
Other name for Typical Antipsychotic drugs
1st Generation
Other name for Atypical Antipsychotic drugs
2nd Generation
Rare condition in which there is lack of WBC production when taking antipsychotic meds
Agranulocytosis
Signs of agranulocytosis
Fever, cough (flu-like)
Septic shock ( rapid pulse, hypotension)
Swollen painful gums
Immediate nursing care for agranulocytosis
Notify HCP first sign of fever
