Anti-Platelet Flashcards
1
Q
Aspirin inhibits 2 enzymes
A
COX1
TXA2
2
Q
Clopidogrel MOA:
A
P2Y12 Antagonist blocks Gi (ADP receptor blocker)
3
Q
cAMP (promotes/inhibits) platelet activation
A
Inhibits
4
Q
Abciximab MAO:
A
Glycoproteins IIb/IIIa inhibitor blocks aggregation of fibrinogen
5
Q
Post angioplasty or PCI (stent) one would administer:
A
Abiciximab
6
Q
Dipyridamole MAO:
A
Phosphodiesterase inhibitors increasing cAMP concentration
7
Q
cAMP causes (vasodilation/vasoconstriction)
A
Vasodilation
8
Q
Dypyridamole can cause
A
Coronary steal phenomena
9
Q
What to use after cardiac valve replacement
A
Dipyridamole
10
Q
Can use for cardiac stress test
A
Dipyridamole
11
Q
Absorption is acid dependent in what platelet inhibitors?
A
Phosphodiesterase inhibitors like dipyridamole
