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PCOL > Anti-microbials > Flashcards

Anti-microbials Flashcards

1
Q

Bacitracin

A

Glycopeptides

Inhibits synthesis or damage to cell wall

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2
Q

Penicillins

A

B-lactam

Inhibits synthesis or damage to cell wall

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3
Q

Cephalosporins

A

B-lactam

Inhibits synthesis or damage to cell wall

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4
Q

Monobactams

A

B-lactams - aztreonam

Inhibits synthesis or damage to cell wall

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5
Q

Carbapenems

A

B-lactams - impenem, panipenem, meropenem

Inhibits synthesis or damage to cell wall

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6
Q

Polymixins

A

Inhibits synthesis or damages cytoplasmic membrane

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7
Q

Daptomycin

A

Inhibits synthesis or damage to cytoplasmic membrane

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8
Q

B-lactamase inhibitors (name and mechanism)

A

Clavulanate, sulbactam, tazobactam

Bacterial cell wall inhibitors

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9
Q

Tetracyclines

A

Tetracycline, doxycycline, minocycline

Inhibits bacterial ribosome actions (protein synthesis)

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10
Q

Macrolides

A

Erythromycin, ketolides

Inhibits bacterial ribosome actions (protein synthesis)

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11
Q

Aminoglycosides

A

Streptomycin, gentamicin, neomycin

Inhibits bacterial ribosomal actions (protein synthesis)

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12
Q

Spectinomycin

A

Inhibits ribosomal actions (protein synthesis)

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13
Q

Clindamycin

A

Inhibits bacterial ribosomal action (protein synthesis)

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14
Q

Mupirocin

A

Inhibits bacterial ribosomal actions (protein synthesis)

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15
Q

Chloramphenicol

A

Inhibits ribosomal actions (protein synthesis)

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16
Q

Streptogramins

A

Inhibits ribosomal actions (protein synthesis)

17
Q

Oxazolidinones

A

Inhibits bacterial ribosomal actions (protein synthesis)

18
Q

Sulfamethoxazole

A

Sulfonamide

Folate antagonist - inhibits dihydropteroate synthase

19
Q

Sulfadiazine

A

Sulfonamide

Folate antagonist - inhibits dihydropteroate synthase

20
Q

Sulfamethizole

A

Sulfonamide

Folate antagonist - inhibits dihydropteroate synthase

21
Q

Sulfasalazine

A

Sulfonamide

Folate antagonist - inhibits dihydropteroate synthase

22
Q

Sulfisoxazole

A

Sulfonamide

Folate antagonist - inhibits dihydropteroate synthase

23
Q

Trimethoprim

A

Bacterial folate antagonist - inhibits dihydrofolate reductase (for THF)

24
Q

Fluoroquinolones

A

Ciprofloxacin, norfloxacin, levofloxacin, gatifloxacin, moxifloxacin
Inhibits/damages bacterial DNA (modification of synthesis or metabolism of NA)

25
Q

Nitrofurans

A

Furazolidone, furaltadone, mitrofurantoin, nitrofurazone

Inhibits/damages bacterial DNA (modification of synthesis/metabolism of NA)

26
Q

Colistin (Polymixins E)

A

Inhibits synthesis/damages to cytoplasmic membranes

27
Q

Polymixin B

A

Inhibits synthesis/damages cytoplasmic membrane

28
Q

Isoniazid

A

Anti- TB drug (first line)

29
Q

Rifampin

A

Anti-TB drug (first line)

30
Q

Rifabutin

A

Anti-TB drug (first line)

31
Q

Rifapentine

A

Anti-TB drug (first line)

32
Q

Pyrazinamide

A

Anti- TB drug (first line)

33
Q

Ethambutol

A

Anti-TB drug (first line)

34
Q

Vancomycin

A

glycopeptides

Inhibits synthesis or damage to cell wall

PCOL (2 decks)

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