Anti-Fungals Flashcards

1
Q

Amphotericin

A

Polyenes

Associates with ergosterol (cell membrane damage)

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2
Q

Ketoconazole

A

Triazole

Inhibits ergosterol synthesis (cell membranes)

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3
Q

Terbinafine

A

Inhibits ergosterol biosynthesis (cell membrane)

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4
Q

Griseofulvin

A

Inhibits mitosis by interacting with microtubules (nuclear division)

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5
Q

Flucytosine

A

NA synthesis (inhibits RNA and DNA synthesis)

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6
Q

Itraconazole

A

Triazole

Inhibits 14alpha-demethylase

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7
Q

Fluconazole

A

Triazole

Inhibits 14alpha-demethylase (ergosterol synthesis)

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8
Q

Nystatin

A

Polyenes

Associates with ergosterol (cell membranes0

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9
Q

Caspofungin

A

Blocks synthesis of 1-3-beta-D-glucan (cell wall component)

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