Anti-Fungals Flashcards
1
Q
Amphotericin
A
Polyenes
Associates with ergosterol (cell membrane damage)
2
Q
Ketoconazole
A
Triazole
Inhibits ergosterol synthesis (cell membranes)
3
Q
Terbinafine
A
Inhibits ergosterol biosynthesis (cell membrane)
4
Q
Griseofulvin
A
Inhibits mitosis by interacting with microtubules (nuclear division)
5
Q
Flucytosine
A
NA synthesis (inhibits RNA and DNA synthesis)
6
Q
Itraconazole
A
Triazole
Inhibits 14alpha-demethylase
7
Q
Fluconazole
A
Triazole
Inhibits 14alpha-demethylase (ergosterol synthesis)
8
Q
Nystatin
A
Polyenes
Associates with ergosterol (cell membranes0
9
Q
Caspofungin
A
Blocks synthesis of 1-3-beta-D-glucan (cell wall component)