Anti-Fungal Flashcards
Yeast infection
Unicellular
Candida alibicans
Mold infection
Multicellular
Aspergillus
Fungi cell membrane is made of
Ergosterol
Nystatin
Used topically to treat candida infections of mouth, vaginal thrush, diaper rash
Amphotericin B
Broad spectrum
IV to treat candida spp. Aspergillus spp. M, histoplasmosis
Commonly used IV infusion in combo w flucytocine to treat cryptococcal meningitis
Orally to treat fungal infection of upper git
Nephrotoxicity
Hypokalemia
Thrombophlebitis ( change site)
Liposomal amphotericin B
Lower nephrotoxicity
Ketoconazole
Topically superficial mycoses eg candida and dermatophytes infec.
Orally to treat systemic mycoses eg candida infect and blastomycosis
(Flu)
Topical shampoo
Hepatotoxicity
Gynecomastia
Miconazole
Topically to cure superficial infections( tinea, capitis, corpris and pedis)
Vaginal cream to treat vulvovahinal candida infections
Irritation and burning sensation
Fluconazole
Variety of anti fungal infections eg IV for fungal meningitis Orally for candida infection of the vagina Ineffective against aspergillosis Hepatotoxicity SJS
Terbinafine
Rapidly absorbed by skin nails
Topically and orally to treat skin and nail infections like griseofulvin
Caspofungin
Slow IV infusion for candida infections include candidemia, intra-abdominal abscesses and pleural cavity infections
Invasive aspergillosis in RF Patients
Infused vein complication
Septic shock
Hypotension
Respiratory failure
Griseofulvin
Orally for dermatophyte infections of nails and skin like tinea capitis tinea corpis tinea pedis
Photosensitivity
CI pregnant
Flucytosine
IV for serve endocarditis and UTI caused by candida Albicans
Pneumonia and meningitis caused by cryptococcus neoformans
Commonly used in combo w amphotericin B
Thrombocytopenia
Alopecia
