anti-epliptic

Question 1

Adjacent in partial seizure for neuropathic pain

Answer 1

Gabapentin

Question 2

Gabapentin AE

Answer 2

Somnolence (sleepy)

Question 3

Modifies the synaptic release of GABA & glutamate

Answer 3

Levetiracetam

Question 4

Used alone or adjacent therapy of Focal onset, mycolnic & primary generalized tonic-clonic seizures

Answer 4

Levetiracetam

Question 5

Levetiracetam AE

Answer 5

Mood alteration

Question 6

Add-on or mono-therapy in partial seizures, generalized tonic-clonic seizures.

Answer 6

Lamotrigine

Question 7

Adjacent therapy with valproate

Answer 7

Lamotrigine

Question 8

Lamotrigine AE

Answer 8

Steven Johnson syndrome

Question 9

Blocks GABA reuptake

Answer 9

Tiagabine

Question 10

Adjacent therapy for partial seizures & generalized tonic-clonic seizures

Answer 10

Tiagabine

Question 11

Blocks Na+ channels
Blocks T-type CA++

Answer 11

Zonisamide

Question 12

Adjacent therapy in partial seizures

Answer 12

Zonisamide

Question 13

Zonisamide AE

Answer 13

Allergic reaction

Question 14

Blocking voltage dependent Na+ channels
Potentiate inhibitory effect of GABA

Answer 14

Topiramate

Question 15

Monotherapy for partial or generalized seizures

Answer 15

Topiramate

Question 16

Topiramate AE

Answer 16

WEIGHT LOSS

Question 17

multiple mechanisms including:
blocking of voltage-dependent Na+ channels
Blocks NMDA receptors
Blocks Ca+ channels
Potentiate GABA action

Answer 17

Felbamate

Question 18

Third line broad spectrum (refractory case)

Answer 18

Felbamate

Question 19

Felbamate AE

Answer 19

Aplastic anemia
Severe hepatitis

Question 20

Management of status epilepticus:
1- (?)
2- check pulse, bp, glucose and respiratory rate
3- secure intravenous access
4- send blood for: glucose, urea, electrolytes, calcium, magnesium, liver function, anti epileptic levels
5- correct any metabolic trigger like hypoglycemia

Answer 20

1- ensure airway is patent and give oxygen to

Question 21

Management of status epilepticus:
1- ensure airway is patent and give oxygen to prevent cerebral hypoxia
2- (?)
3- secure intravenous access
4- send blood for: glucose, urea, electrolytes, calcium, magnesium, liver function, anti epileptic levels
5- correct any metabolic trigger like hypoglycemia

Answer 21

2- check pulse, bp, glucose and respiratory rate

Question 22

Management of status epilepticus:
1- ensure airway is patent and give oxygen to prevent cerebral hypoxia
2- check pulse, bp, glucose and respiratory rate
3- (?)
4- send blood for: glucose, urea, electrolytes, calcium, magnesium, liver function, anti epileptic levels
5- correct any metabolic trigger like hypoglycemia

Answer 22

3- secure intravenous access

Question 23

Management of status epilepticus:
1- ensure airway is patent and give oxygen to prevent cerebral hypoxia
2- check pulse, bp, glucose and respiratory rate
3- secure intravenous access
4- (?)
5- correct any metabolic trigger like hypoglycemia

Answer 23

4- send blood for: glucose, urea, electrolytes, calcium, magnesium, liver function, anti epileptic levels

Question 24

Management of status epilepticus:
1- ensure airway is patent and give oxygen to prevent cerebral hypoxia
2- check pulse, bp, glucose and respiratory rate
3- secure intravenous access
4- send blood for: glucose, urea, electrolytes, calcium, magnesium, liver function, anti epileptic levels
5- (?)

Answer 24

5- correct any metabolic trigger like hypoglycemia

Question 25

Given if seizure last >5mins

Answer 25

Diazepam 10mg IV or rectally
Or lorazepam 4mg IV