Anti Epileptics Flashcards
1st & 2nd choice in grand-mal epilepsy
Phenytoin
Enzyme inducer
Phenytoin
Not given IM because it will cause tissue damage
Phenytoin
Phenytoin AE
Hirsutism
NDA
Megaloblastic anemia
Gingival hyperplasia
Teratogenic
1st line choice of partial seizures
Carbamazepine
Causes Auto induction
Carbamazepine
Carbamazepine AE
NDA
WATER RETENTION
HYPONATERMIA
Exaburates absence seizure
Carbamazepine
Blocks Na+ influx
Blocks GABA-transaminase
Valproate
Enzyme inhibitor
Valproate
Valproate AE
Hair loss
Hepatotoxicity
Spina bifida
Blocks T-type Ca+
Ethasuximide
1st line choice for absence seizures
Ethosuximide
Least toxic AED
Ethosuximide
Inc. GABA & prolong Cl- opening
Phenobarbital
2nd choice for grand-mal epilepsy
Phenobarbital (1st or 2nd choice is phenytoin)
Bind to GABA receptors
Benzodiazepines
- Drug of choice in grand-mal epilepsy (status epileptics)
- febrile convulsion in children
Benzodiazepines