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CNS Pharma > Anti Epileptics > Flashcards

Anti Epileptics Flashcards

1
Q

1st & 2nd choice in grand-mal epilepsy

A

Phenytoin

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2
Q

Enzyme inducer

A

Phenytoin

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3
Q

Not given IM because it will cause tissue damage

A

Phenytoin

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4
Q

Phenytoin AE

A

Hirsutism
NDA
Megaloblastic anemia
Gingival hyperplasia
Teratogenic

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5
Q

1st line choice of partial seizures

A

Carbamazepine

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6
Q

Causes Auto induction

A

Carbamazepine

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7
Q

Carbamazepine AE

A

NDA
WATER RETENTION
HYPONATERMIA

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8
Q

Exaburates absence seizure

A

Carbamazepine

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9
Q

Blocks Na+ influx
Blocks GABA-transaminase

A

Valproate

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10
Q

Enzyme inhibitor

A

Valproate

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11
Q

Valproate AE

A

Hair loss
Hepatotoxicity
Spina bifida

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12
Q

Blocks T-type Ca+

A

Ethasuximide

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13
Q

1st line choice for absence seizures

A

Ethosuximide

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14
Q

Least toxic AED

A

Ethosuximide

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15
Q

Inc. GABA & prolong Cl- opening

A

Phenobarbital

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16
Q

2nd choice for grand-mal epilepsy

A

Phenobarbital (1st or 2nd choice is phenytoin)

17
Q

Bind to GABA receptors

A

Benzodiazepines

18
Q
  • Drug of choice in grand-mal epilepsy (status epileptics)
  • febrile convulsion in children
A

Benzodiazepines

CNS Pharma (2 decks)

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