Anti-diabetics Flashcards
Lispro (Humalog)
Apart (Novolog)
Glulisine (Apidra)
are _____ action drugs = a short duration
Rapid
Regular (Huminlin R, Novolin R)
are ______ acting = slower acting drugs
Short
Neutral Protamine Hagedorn (NPH) have an __________ duration.
Intermediate
Detemir (Levir)
Glargine (Lantus)
have a ______ duration (basal insulin)
Long
Degludec (Tresbia) is ________ acting (basal insulin analogue)
Utralong
_______ acting insulin
Used as nutritional insulin and must be given prior to mealtime.
Rapid:
Lispro (Humalog)
Apart (Novolog)
Glulisine (Apidra)
_______ insulin can be given about 30 minutes before mealtime
Regular
What insulin?
Dosing is often given twice a day (before breakfast and supper) in combination with short acting insulin.
(clear-cloudy mixing)
Neutral Protamine Hagedorn (NPH)
Dosing given as basal insulin coverage - Rapid or short-acting insulins are added for mealtime coverage.
Detemir (Levir)
Glargine (Lantus)
Degludec (Tresbia)
(Non-Insulin Injectables)
Supplement to mealtime insulin for both type 1 and type 2 diabetics
Actions: reduces postprandial glucose levels by delaying gastric emptying and decreasing the release of glucagon
Adverse Effects: risk of hypoglycemia when administered with insulin
Considerations: Dosing is prior to major meals
Amylin Mimetics
pramlintide (Symlin)
which drug causes the pancreas to produce more insulin?
Sulfonylureas
Glipizide (Glucotrol)
Glyburide (Micronase)
Glimepride (Amaryl)
Zide Ride Pride
Which drugs are given w/ meals?
????
Rapid:
Lispro (Humalog)
Apart (Novolog)
Glulisine (Apidra)
RegularMeglitinides:
(-linide)
Repaglinide (Prandin)
Nateglinide (Starlix)
Clear fluid, given subQ/IV
Rapid
*Controls postprandial (PP) rise in glucose
Given before and after meals
Lispr
Clear fluid, given subQ/IV
Rapid
*Control postprandial risk in glucose
Given before meals
Aspart
Human insulin, given dubQ/IV
Slower
(stop giving when glucose = 250, not 110)
Regular