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Pharmacology > Anti-diabetics > Flashcards

Anti-diabetics Flashcards

1
Q

Lispro (Humalog)
Apart (Novolog)
Glulisine (Apidra)

are _____ action drugs = a short duration

A

Rapid

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2
Q

Regular (Huminlin R, Novolin R)

are ______ acting = slower acting drugs

A

Short

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3
Q

Neutral Protamine Hagedorn (NPH) have an __________ duration.

A

Intermediate

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4
Q

Detemir (Levir)
Glargine (Lantus)
have a ______ duration (basal insulin)

A

Long

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5
Q

Degludec (Tresbia) is ________ acting (basal insulin analogue)

A

Utralong

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6
Q

_______ acting insulin

Used as nutritional insulin and must be given prior to mealtime.

A

Rapid:
Lispro (Humalog)
Apart (Novolog)
Glulisine (Apidra)

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7
Q

_______ insulin can be given about 30 minutes before mealtime

A

Regular

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8
Q

What insulin?

Dosing is often given twice a day (before breakfast and supper) in combination with short acting insulin.

(clear-cloudy mixing)

A

Neutral Protamine Hagedorn (NPH)

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9
Q

Dosing given as basal insulin coverage - Rapid or short-acting insulins are added for mealtime coverage.

A

Detemir (Levir)
Glargine (Lantus)
Degludec (Tresbia)

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10
Q

(Non-Insulin Injectables)

Supplement to mealtime insulin for both type 1 and type 2 diabetics

Actions: reduces postprandial glucose levels by delaying gastric emptying and decreasing the release of glucagon

Adverse Effects: risk of hypoglycemia when administered with insulin

Considerations: Dosing is prior to major meals

A

Amylin Mimetics

pramlintide (Symlin)

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11
Q

which drug causes the pancreas to produce more insulin?

A

Sulfonylureas

Glipizide (Glucotrol)
Glyburide (Micronase)
Glimepride (Amaryl)

Zide Ride Pride

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12
Q

Which drugs are given w/ meals?

????

A

Rapid:
Lispro (Humalog)
Apart (Novolog)
Glulisine (Apidra)

RegularMeglitinides:
(-linide)
Repaglinide (Prandin)
Nateglinide (Starlix)

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13
Q

Clear fluid, given subQ/IV

Rapid

*Controls postprandial (PP) rise in glucose

Given before and after meals

A

Lispr

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14
Q

Clear fluid, given subQ/IV

Rapid

*Control postprandial risk in glucose

Given before meals

A

Aspart

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15
Q

Human insulin, given dubQ/IV
Slower
(stop giving when glucose = 250, not 110)

A

Regular

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16
Q

Cloudy fluid

Intermediate

NOT given at mealtime to control postprandial hyperglycemia

Given in combo with short-acting
(clear-cloudy)

A

NPH (neutral protamine hagedorn)

17
Q

Hypoglycemia
lipohyperthrophy
hypokalemia

are what?

A

Adverse effects of insulins

18
Q
  • thiazides
  • steriods
  • sympathomimetics

> > _________ glucose

19
Q
  • sulfonylueras
  • glinides
  • alcohol

are __________ (additive)

A

synergeristic

20
Q

Onset: 15-30 min
Peak: 30-150 min
Duration: 3-6.6 hr

21
Q

Onset: 10-20 min
Peak: 60-180 min OR 1-3 hours
Duration: 3-5 hours

22
Q

Onset: 10-15 min
Peak: 30-90min (1.5 hours)
Duration: 3-5 hours

Pharmacology (6 decks)

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