Anti-biotic Drugs Flashcards

1
Q

what additional drug do the beta-lactam drugs need to make the drug more powerful against those MOs?

A

BETA-LACTAMASE INHIBITOR

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2
Q

He discovered the mold that produced Penicillin which was the first antibiotic to be used and marketed

A

Alexander Fleming

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3
Q

primarily effective against one type of organism (selective)

A

NARROW SPECTRUM

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4
Q

effective against gram-positive and gram-negative organisms

A

BROAD SPECTRUM

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5
Q

this is the drug of choice for gram-positive cocci (such as Streptococcus pneumonia, viridian, and pyogenes), meningitis caused by gram-negative cocci, Neisseria meningitides and for syphilis caused by Spirochete treponema pallidum

A

PENICILLINS

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6
Q

MEC means?

A

Minimum Effective Concentration

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7
Q

a bioassay performed on the skin which detects the presence of allergen-specific IgEon a patient’s mast cells

A

Skin testing

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8
Q

you have to limit the consumption of this drug if the patient have prosthetic heart valves and recurring urinary tract infections

A

PROPHYLACTIC

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9
Q

Enumerate the Five Mechanisms of Antibacterial Action

A

1) inhibition of bacterial cell-wall synthesis
2) alteration of membrane permeability
3) inhibition of protein synthesis; 4) inhibition of the synthesis of bacterial RNA and DNA
5) interference with metabolism within the cell

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10
Q

The patient who took penicillin has hyperkalemia what nursing intervention should you do?

A

Monitor cardiac status and electrolytes levels

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11
Q

this kind of drug penetrates the bacterial cell wall and have an affinity for the bacteria’s binding sites

A

Antibacterial Drugs

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12
Q

what are the anti-biotic combinations?

A
  1. ADDITIVE EFFECT
  2. POTENTIATIVE EFFECT
  3. ANTAGONISTIC EFFECT
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13
Q

DOC for Rickettsia, Chlamydia and Mycoplasma, spirochetes such as syphilis and Lyme

A

TETRACYCLINES

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14
Q

this drug is prescribed to patients who are allergic to penicillins

A

MACROLIDES

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15
Q

What should you do when the patient who took Macrolides had ototoxicity with high-dose therapy?

A

Monitor for hearing loss, vertigo, and ringing in the ear. then notify the provider if these occur.

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16
Q

This drug should be administered
in oral preparation on an empty stomach (1hr before or 2 hrs after) with a full glass of water unless with GI distress

A

Azithromycin (MACROLIDES)

17
Q

most effective antimalarial drug for eradicating the parasite during the exoerythrocytic phase

A

PRIMAQUINE

18
Q

when the antifolate drugs (methotrexate, sulfonamides) are mixed or added to Pyrimethamine what happens?

A

the bone marrow suppression increases

19
Q

These kinds of drugs are very specific with the worms they can kill, thus accurate identification of causative organisms prior to treatment is necessary

A

anti-helminthic drugs

20
Q

This drug increases the permeability of the cell membrane of the worm which causes dislodgement on the site of residence which they are then killed by the host

A

Praziquantel