Anti Arrhythmic Drugs Flashcards
Class I
Na channel Blockers
Diso pyramide Flecainide Lidocaine Mexiletine Procainamide Propafenone Quinidine
Class II
B- adrenoreceptor Blockers
Esmolol
Metorpolol
Propranolol
Class III
K channel blockers
Amiodarone
Dofetilide
Dronedarone
Sotalol
Class IV
Ca Channel blockers
Diltiazem
Verapamil
Other anti arrhythmics
Adenosine
Digoxin
Class IA mech of action
Na channel blockers
Slow phase 0 depolarization in ventricular muscle fibres
Class IB mech of action
Na channel blockers
Shortens Phase 3 repolarization in ventricular muscle fibres
Class IC Mech of action
Na channel blockers
Markedly slows phase 0 depolarization in ventricular muscle fibres
Class II mech of action
B blockers
Inhibits phase 4 depolarization in SA and AV nodes
Class III mech of action
K channel blockers
Prolongs Phase 3 repolarization in ventricular muscle fibres
Class IV mech of Action
Ca Channel Blockers
Inhibits action potential in SA and AV nodes
Class 1 a Na channel blockers (moderate blockers)
Disopyramide
Quinidine
Procainamide
Class 1b Na channel blockers (weak blockers)
Lidocaine
Mexiletine
For prevention of ventricular tachycardia as 2nd 3rd line agents
Class 1c Na channel blockers (strong blockers)
Flecainide (pill in the pocket)
Propafenone