Anti-Anginals

Question 1

3 classes of drugs used to treat angina

Answer 1

1. Nitrates - veins (pre load)
2. Beta blockers - heart
3. Ca channel blockers - arteries (after load)

Question 2

3 types of nitrates

Answer 2

1. Nitroglycerin
2. Isosorbide dinitrate
3. Isosorbide mononitrate

Question 3

Nitrate side effects

Answer 3

Vasodilation related effects

1. headache
2. flushing
3. hypotension (orthostatic)
4. reflex tachycardia

Question 4

2 types of Ca channel blockers

Answer 4

1. dihydropyridines

2. non-dihydropyridines

Question 5

Location of effect fo the 2 types of calcium channel blockers

Answer 5

1. non-dihydro - verapamil, diltizaem - relax heart

2. dihydro - amlodipine, nifedipine - relax blood vessels

Question 6

What type of angina do dihydropyridines treat?

Answer 6

Vasospastic angina

Also treat hypertension + cardiac arrhythmias

Question 7

What do non-dihydropyridines treat?

Answer 7

Hypertension + cardiac arrythmias

Question 8

What are two types of beta blockers used to treat angina?

Answer 8

Propanolol

Metoprolol

Question 9

Which type of angina is propranolol contraindicated in?

Answer 9

Vasospastic angina