Anterior Pituitary Flashcards
Six major hormones produced
PRL GH ACTH FSH LH TSH
Blood supply to pituitary
Hypohpyseal arteries:
Superior-
Inferior- posterior pituitary
Which of the following is true regarding prolactin:
A. Produced by somatotropes
B. Secretion is non pulsatile
C. Central control mechanisms is non inhibitory
D. D2 receptors mediate inhibition of prolactin synthesis
D.
A. Produced by lactotropes
B. Secretion is pulsating
C. Central control mechanisms is inhibitory
D. D2 receptors mediate inhibition of prolactin synthesis
Which of the following inhibit PRL secretion A. Glucocorticoid B. TRH C. Vasoactive intestinal peptide D. Acute MI
Glucocorticoids and Thyroid hormones
True of prolactin action: A. Promoted GNRH release B. Promotes folliculogenesis C. Has a luteolytic effect D. Promotes granulosa cell aromatase activity
C
A. Inhibits GNRH release
B. Inhibits folliculogenesis
C. Has a luteolytic effect
D. Inhibits granulosa cell aromatase activity
Most abundant anterior pituitary hormone
Growth hormone
Pituitary stalk section due to head traumatic or compressive mass lesions at the skull base can lead to hyper secretion of this hormone
Prolactin
Peripheral target hormone for GH
IGF-1
GH receptor antagonist approved for treatment of acromegaly
Peg is Omana
True of GH: A. Highest peak levels occur during the day B. GH is reduced in the malnourished C. Glucose load suppresses GH D. Progesterone induces GH
C
A. Highest peak levels occur during the night
B. GH is reduced in the obese
C. Glucose load suppresses GH
D. Estrogen induces GH
True of GH function: A. Induces nitrogen excretion B. Antagonizes insulin action C. Reduces protein synthesis D. Prevents lypolysis
B
A. Induces nitrogen retention
B. Antagonizes insulin action
C. Induces protein synthesis
D. Stimulates lypolysis
Major source of circulating IGF-1
Liver
