Antepartum Fetal Surveillance Flashcards
Risk factors for fetal death
Maternal
- Antiphospholipid syndrome
- Hyperthyroidism
- Hemoglobinopathies
- Cyanotic heart disease
- Lupus
- Chronic renal disease
- Type 1 diabetes mellitus
- Hypertensive disorders
Pregnancy-related complications
- GHTN/ pre-eclampsia*
- Oligohydramnios
- Polyhydramnios
- Decreased fetal movement
- Intrauterine (fetal) growth restriction
- Post-term pregnancy
- Isoimmunization
- Previous fetal demise
- Multiple gestation with growth discordancy
Maternal → fetal oxygen transfer
Environment → Lungs → Heart → Vasculature → Uterus → Placenta → Umbilical Cord → Fetus
Fetal effects of oxygen pathway interruption
Hypoxemia → Hypoxia → Metabolic Acidosis → Metabolic Acidemia → Hypotension
Fetoplacental circulation key points
- Umbilical vein carries oxygenated blood to fetus
- Umbilical arteries carry deoxygenated blood to placenta
- Blood is shunted via the:
- Ductus venosus - shunts blood away from the liver (portal vein) to IVC
- Ductus arteriosus - shunts blood away from lungs (via pulmonary artery) to aorta
- Foramen ovale - shunts blood across the atrial septum (RA → LA) → more oxygenated blood to body
What is the difference between hypoxia and hypoxemia?
Decreased O2 concentration in the
- Hypoxia - tissue
- Hypoxemia - blood
Hypercapnia
More than the normal level of carbon dioxide in the blood
What is the difference between acidosis and acidemia?
Increased hydrogen ion concentration:
- Acidemia - blood
- Acidosis - tissue
Glucose metabolism
(aerobic vs anaerobic, biproducts)
- Glucose → pyruvate, no O2 needed
- Pyruvate → ATP +
- CO2 (aerobic) or
- lactic acid (anaerobic)
- does not cross placenta easily
Fetal metabolic acidemia
- Pyruvic acid → lactic acid + ATP
- Buffer base consumed (HCO3, plasma proteins, Hgb, inorganic phosphate) → base deficit
- Cure: increase fetal oxgenation
Complications of fetal acidemia
- Seizure disorders
- Developmental delays
- Cerebral palsy
- Fetal/neonatal death
Neonatal encephalopathy
Clinically defined syndrome of disturbed neurological function in term and near term infants
- Respiratory difficulty
- Depression of tone, reflexes
- Subnormal LOC
- Often seizures
Hypoxic-ischemic encephalopathy
- a subset of neonatal encephalopathy
- result of a hypoxic/anoxic episode
- accumulation of lactic and carbonic acids (H+ ions) in the blood
Uterine tachsystole
- > 5 contractions in 10 minutes averaged over 30 minutes
- Abnormal contraction pattern
- Can affect fetal oxygen exchange
Fetal heart rate baseline
- FHR during a 10 minute segment rounded to nearest 5 beats, excluding periods of marked variability/periodic/episodic changes
Normal fetal heart rate range
110 - 160 bpm
Fetal tachycardia
Baseline > 160 bpm