Antenatal Screening Flashcards
What is the purpose of antenatal screening? (2)
Detect risk of disorders such as Down’s syndrome, cystic fibrosis, muscular dystrophy
Determine sex of baby
Example of antenatal tests
Ultra sound
Rhesus antibody testing
Amniocentesis
Chronic villus sampling
Two stages of ultrasound
1- dating scan (8-14 weeks)
-determine age and due date
2- anomaly scan (18-20 weeks)
- physical developments
Biochemical tests
Detects marker chemicals produced during physiological changes of pregnancy
Amniocentesis weeks
15th-18th week
Amniocentesis advantages
Prenatal diagnosis
Detects neural tube defects
Amniocentesis disadvantages
Small miscarriage risk
Gives later results
Chronic villus sampling weeks
11th-14th week
Chronic villus sampling advantages
Prenatal diagnosis
Earlier results
Chronic villus sampling disadvantages
Not detect newest tube defect
Small miscarriage risk
Carry risk of defects to fingers and toes if carried out too early
Karyotype
Image of chromosomes
Arranged in homologous pairs
Used to identify anomalies in structure and numbers of proteins
Rhesus anti body testing blood types
Mother is negative
Get us is positive
What happens in rhesus
- Fetus red blood cells cross the placenta
- This trigger the release of mothers antibodies
- antibodies can cross into feral blood & cause blood clot
Rhesus antibody treatment
•given Anti rhesus antibodies after 1st pregnancy - so that rhesus positive blood cells are destroyed before discovered by mothers immune
-protects from rhesus negative baby