Antenatal prophylactic antibiotics for women with P‑PROM

Question 1

Antenatal prophylactic antibiotics for women with P‑PROM

Answer 1

• Offer women with P-PROM oral erythromycin 250 mg 4 times a day[1] for a maximum of 10 days or until the woman is in established labour (whichever is sooner).
• For women with P‑PROM who cannot tolerate erythromycin or in whom erythromycin is contraindicated, consider oral penicillin for a maximum of 10 days or until the woman is in established labour (whichever is sooner).
• Do not offer women with P‑PROM co‑amoxiclav as prophylaxis for intrauterine infection